Research project title

Investigating and predicting structural and physicochemical properties of lipid nanoparticles (LNPs)

Education level

Doctorate

Director/co-director

Director: Marc Lavertu

End of display

June 30, 2026

Areas of expertise

Biomedical engineering

Materials science and technology

Unit(s) and department(s)

Department of Chemical Engineering

Conditions

Send your application to anik.chevrier@polymtl.ca

Detailed description

This project aims to develop a comprehensive understanding of the structural and physicochemical properties of lipid nanoparticles (LNPs) by leveraging cutting-edge experimental characterization approaches and modeling their critical quality attributes (CQAs). The PhD candidate will work to link multi-scale measurements—from molecular organization to nanometric structure—to predictive models that shed light on the stability, heterogeneity, and evolution of LNPs under different formulation conditions. The project will benefit from a unique technological environment, including advanced formulation tools and a specialized analytical suite (e.g., EAF4-MALS, Stunner, Nanosight). This research offers a unique opportunity to contribute to the fundamental understanding of complex nanoparticle systems while developing new analytical and conceptual approaches. The position is aimed at someone from a physics, engineering physics or related field, interested in the modeling, experimental characterization and analysis of nanostructured systems.

Financing possibility

Project funded by an NSERC/Discovery grant