Marc Lavertu
B.Eng. (Poly), M.Eng. (Poly), Ph.D. Génie Biomedical (Poly)
Associate Professor
Department of Chemical Engineering
Department of Chemical Engineering
Primary sphere of excellence in research
Human Health
Human Health
Secondary sphere(s) of excellence in research
Innovative Materials
Innovative Materials
Research interests and affiliations
Research interests
- Gene delivery
- Biopolymers
- Chitosan
- Nanoparticles
- Nanomedicine
- Regenerative medicine
- Biomaterials
- mRNA
Affiliation(s)
- Institut de génie biomédical, Member
- Institut de génie biomédical, Member
Expertise type(s) (NSERC subjects)
- 1900 BIOMEDICAL ENGINEERING
- 1902 Biomedical materials
- 1901 Biomedical technology
- 2006 Biomaterials
- 3754 Biopolymers
Publications
Recent publications
Journal article
Journal article
Journal article
Journal article
Alameh, M.-G., Semon, A., Bayard, N. U., Pan, Y.-G., Dwivedi, G., Knox, J., Glover, R. C., Rangel, P. C., Tanes, C., Bittinger, K., She, Q., Hu, H., Bonam, S. R., Maslanka, J. R., Planet, P. J., Moustafa, A. M., Davis, B., Chevrier, A., Beattie, M., ... Zackular, J. P. (2024). A multivalent mRNA-LNP vaccine protects against Clostridioides difficile infection. Science, 386(6717), 69-75.
Alameh, M.‐G., Naeini, A. T., Dwivedi, G., Lesage, F., Buschmann, M. D., & Lavertu, M. (2024). Chitosan siRNA nanoparticles produce significant non-toxic functional gene silencing in Kidney Cortices. Polymers, 16(17), 2547 (22 pages).
BenDavid, E., Ramezanian, S., Lu, Y., Rousseau, J., Schroeder, A., Lavertu, M., & Tremblay, J. P. (2024). Emerging perspectives on prime editor delivery to the brain. Pharmaceuticals, 17(6), 763 (42 pages).
Chevrier, A., & Lavertu, M. (2024). Manufacturing process affects coagulation kinetics of Ortho-R, an injectable chitosan–platelet-rich plasma biomaterial for tissue repair. Bioengineering, 11(9), 929 (10 pages).
See all publications (77)
Supervision at Polytechnique
COMPLETED
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Ph.D. Thesis (6)
- Ghazi Zadeh, L. (2018). Freeze-Dried Chitosan Platelet-Rich Plasma Mixtures for Knee Meniscus Repair [Ph.D. thesis, École Polytechnique de Montréal].
- Mathieu, C. (2018). The Role of Biomaterials in Synovial Joint Inflammation and Chondrogenesis Towards the Development of a Novel Post-Surgical Articular Cartilage Repair Therapy [Ph.D. thesis, École Polytechnique de Montréal].
- Alameh, M. (2017). Gene Silencing Using Chitosan Based siRNA Delivery Systems in Cells and Animals [Ph.D. thesis, École Polytechnique de Montréal].
- TavakoliNaeini, A. (2017). Large Scale Production, Purification, and Modification of Chitosan-Based Complexes for Gene Therapy [Ph.D. thesis, École Polytechnique de Montréal].
- Pickenhahn, V. (2016). Transformation régiosélective du chitosane par thioacétylation pour applications biomédicales [Ph.D. thesis, École Polytechnique de Montréal].
- Veilleux, D. (2016). Lyophilisation et concentration de complexes chitosane/ADN et chitosane/ARNic pour la thérapie génique [Ph.D. thesis, École Polytechnique de Montréal].
- Ghazi Zadeh, L. (2018). Freeze-Dried Chitosan Platelet-Rich Plasma Mixtures for Knee Meniscus Repair [Ph.D. thesis, École Polytechnique de Montréal].
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Master's Thesis (4)
- Leroy, P. (2023). Échafaudage cellulaire en nanofibres de polymère et verre bioactif pour la guérison des plaies diabétiques [Master's thesis, Polytechnique Montréal].
- Jeandupeux, E. (2018). Utilisation de l'acide poly (propyl acrylique) pour augmenter l'efficacité in vitro des nanoparticules à base de chitosane et ARN messager [Master's thesis, École Polytechnique de Montréal].
- Soliman, O. Y. (2018). Développement de complexes polyélectrolytes à base d'acide hyaluronique et de chitosane pour la livraison d'ARN messager [Master's thesis, École Polytechnique de Montréal].
- Niebel, Y. (2013). Analyse des complexes oligodésoxyribonucléotide/chitosan par ultracentrifugation analytique [Master's thesis, École Polytechnique de Montréal].