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Marc Lavertu
B.Eng. (Poly), M.Eng. (Poly), Ph.D. Génie Biomedical (Poly)
Expert

Phone: (514) 340-4711 Ext. 3609 Fax: (514) 340-4159 Room: J-2069

Research interests and affiliations

Research interests
  • Gene delivery
  • Biopolymers
  • Chitosan
  • Nanoparticles
Affiliation(s)
Expertise type(s) (NSERC subjects)
  • 1900 BIOMEDICAL ENGINEERING
  • 1902 Biomedical materials

Publications

Recent publications
Patent
Buschmann, M.D., Lavertu, M., Nelea, M., Darras, V., Alameh, M.G., Chevrier, A., Tran-Khanh, N., Naeini Tavakoli, A. & Veilleux, D. (2018). Coated chitosan-based polyplex for delivery of nucleic acids (Patent No US 20180028458 - Application). Retrieved from https://patents.google.com/patent/US20180028458
Journal article
Chevrier, A., Darras, V., Picard, G., Nelea, M., Veilleux, D., Lavertu, M., Hoemann, C.D. & Buschmann, M.D. (2018). Injectable chitosan-platelet-rich plasma (PRP) implants to promote tissue regeneration: In vitro properties, in vivo residence, degradation, cell recruitment and vascularization. Journal of Tissue Engineering and Regenerative Medicine, 12(1), 217-228. Retrieved from https://doi.org/10.1002/term.2403
Journal article
Veilleux, D., Gopalakrishna Panicker, R.K., Chevrier, A., Biniecki, K., Lavertu, M. & Buschmann, M.D. (2018). Lyophilisation and concentration of chitosan/siRNA polyplexes: Influence of buffer composition, oligonucleotide sequence, and hyaluronic acid coating. Journal of Colloid and Interface Science, 512, 335-345. Retrieved from https://doi.org/10.1016/j.jcis.2017.09.084
Journal article
Alameh, M., Lavertu, M., Tran-Khanh, N., Chang, C.Y., Lesage, F., Bail, M., Darras, V., Chevrier, A. & Buschmann, M.D. (2018). siRNA delivery with chitosan: influence of chitosan molecular weight, degree of deacetylation, and amine to phosphate ratio on in vitro silencing efficiency, hemocompatibility, biodistribution, and in vivo efficacy. Biomacromolecules, 19(1), 112-131. Retrieved from https://doi.org/10.1021/acs.biomac.7b01297

Supervision at Polytechnique

COMPLETED

  • Ph.D. Thesis (4)

    • Alameh, M. (2017). Gene Silencing Using Chitosan Based siRNA Delivery Systems in Cells and Animals (Ph.D. Thesis, École Polytechnique de Montréal). Retrieved from https://publications.polymtl.ca/2687/
    • TavakoliNaeini, A. (2017). Large Scale Production, Purification, and Modification of Chitosan-Based Complexes for Gene Therapy (Ph.D. Thesis, École Polytechnique de Montréal). Retrieved from https://publications.polymtl.ca/2667/
    • Pickenhahn, V. (2016). Transformation régiosélective du chitosane par thioacétylation pour applications biomédicales (Ph.D. Thesis, École Polytechnique de Montréal). Retrieved from https://publications.polymtl.ca/2387/
    • Veilleux, D. (2016). Lyophilisation et concentration de complexes chitosane/ADN et chitosane/ARNic pour la thérapie génique (Ph.D. Thesis, École Polytechnique de Montréal). Retrieved from https://publications.polymtl.ca/2263/
  • Master's Thesis (1)

    • Soliman, O.Y. (2018). Développement de complexes polyélectrolytes à base d'acide hyaluronique et de chitosane pour la livraison d'ARN messager (Master's Thesis, École Polytechnique de Montréal). Retrieved from https://publications.polymtl.ca/3121/