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Julien Cohen-Adad
Phd (Paris/Montreal), MSc (Rennes), Eng (Paris)

Research interests and affiliations

Research interests

My lab is developing advanced Magnetic Resonance Imaging (MRI) techniques for quantitative assessment of the brain and spinal cord structure. These developments include hardware (coils), MRI sequences (relaxometry, diffusion tensor imaging, magnetization transfer, functional MRI) and software (multimodal registration, segmentation, motion correction, distortion correction). There is a strong focus on translating research developments into clinics, aiming to improve the diagnosis and prognosis in patients suffering from neurological diseases and traumas. 

The environment is highly multi-disciplinary. We interact with biomedical engineers, physicists, radiologists, neurologists and neurophysiologists. Plus, our lab collaborates with the Martinos Center for Biomedical Imaging at Harvard, therefore some projects will involve travelling to Boston. Projects include:

  • Developing methods for spinal cord MRI in multiple sclerosis (collaboration with Harvard),

  • Studying features of the brain using ultra-high field MRI (collaboration with Harvard),

  • Optimizing MRI acquisition and image processing in patients with spinal cord injury,

  • Programming a pipeline for processing images, with various clinical applications,

  • Building MRI antenna for imaging small animals,

Expertise type(s) (NSERC subjects)
  • 1900 BIOMEDICAL ENGINEERING
  • 1901 Biomedical technology
  • 3102 Nuclear physics
  • 6400 LIFE SCIENCES RESEARCH RELATED TO HUMAN HEALTH AND DISEASE
  • 9000 MEDICAL SCIENCES

Publications

Recent publications
Journal article
Martin, A.R., De Leener, B., Cohen-Adad, J., Cadotte, D.W., Kalsi-Ryan, S., Lange, S.F., Tetreault, L., Nouri, A., Crawley, A., Mikulis, D.J., Ginsberg, H. & Fehlings, M.G. (2017). A Novel MRI Biomarker of Spinal Cord White Matter Injury: T2*-Weighted White Matter to Gray Matter Signal Intensity Ratio. American Journal of Neuroradiology, 38(6), 1266-1273. Retrieved from https://doi.org/10.3174/ajnr.A5162
Journal article
Mingasson, T., Duval, T., Stikov, N. & Cohen-Adad, J. (2017). AxonPacking: An Open-Source Software to Simulate Arrangements of Axons in White Matter. Frontiers in Neuroinformatics, 11, 12 pages. Retrieved from https://doi.org/10.3389/fninf.2017.00005
Journal article
Khoshnejad, M., Roy, M., Martinu, K., Chen, J.I., Cohen-Adad, J., Grondin, S. & Rainville, P. (2017). Brain processing of the temporal dimension of acute pain in short-term memory. Pain, 158(10), 2001-2011. Retrieved from https://doi.org/10.1097/j.pain.0000000000001003
Journal article
Martin, A.R., De Leener, B., Cohen-Adad, J., Cadotte, D.W., Kalsi-Ryan, S., Lange, S.F., Tetreault, L., Nouri, A., Crawley, A., Mikulis, D.J., Ginsberg, H. & Fehlings, M.G. (2017). Clinically Feasible Microstructural MRI to Quantify Cervical Spinal Cord Tissue Injury Using DTI, MT, and T2*-Weighted Imaging: Assessment of Normative Data and Reliability. American Journal of Neuroradiology, 38(6), 1257-1265. Retrieved from https://doi.org/10.3174/ajnr.A5163

Teaching

  • GBM6125
  • GBM6904/7904
  • GBM3318

Supervision at Polytechnique

COMPLETED

  • Master's Thesis (7)

    • Germain, G. (2017). Une antenne hybride RF/shimming pour l'IRM de la moelle épinière (Master's Thesis, École Polytechnique de Montréal). Retrieved from http://publications.polymtl.ca/2623/
    • Saliani, A. (2017). Construction d'un atlas de la microstructure de la matière blanche de la moelle épinière chez le rat à partir d'acquisitions histologiques (Master's Thesis, École Polytechnique de Montréal). Retrieved from http://publications.polymtl.ca/2734/
    • Vuong, M.T. (2017). Comparison of Myelin Imaging Techniques in Ex Vivo Spinal Cord (Master's Thesis, École Polytechnique de Montréal). Retrieved from http://publications.polymtl.ca/2683/
    • Lévy, S. (2016). Caractérisation de la microstructure des voies spinales humaines par IRM multiparamétrique (Master's Thesis, École Polytechnique de Montréal). Retrieved from http://publications.polymtl.ca/2068/
    • Mangeat, G. (2016). Study of Human Cortical Microstructure Using Magnetization Transfer and T2* Mapping with Application in Multiple Sclerosis (Master's Thesis, École Polytechnique de Montréal). Retrieved from http://publications.polymtl.ca/2079/
    • Foias, A. (2015). Design and Construction of a Highly Sensitive Coil for MRI of the Spinal Cord (Master's Thesis, École Polytechnique de Montréal). Retrieved from http://publications.polymtl.ca/2001/
    • De Leener, B. (2014). Segmentation automatique de la moelle épinière sur des images de résonance magnétique par propagation de modèles déformables (Master's Thesis, École Polytechnique de Montréal). Retrieved from http://publications.polymtl.ca/1471

Press review about Julien Cohen-Adad

February 8, 2016, Le Devoir, Les capacités d'apprentissage du système nerveux Image obtenue par résonance magnétique des faisceaux de fibres nerveuses (ou axones) qui descendent dans la moelle épinière et dont les corps cellulaires sont situés dans le cortex cérébral. ( Photo: Laboratoire du professeur Julien Cohen-Adad, École Polytechnique de Montréal).