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Research interests and affiliations

Research interests

My research interests pertain to the development of new technologies in pediatric neuroimaging. More particularly, my research lab focuses on developing open-source software for analyzing brain and spinal cord images acquired with magnetic resonance imaging, using advanced segmentation and registration approaches using machine learning and neurodevelopmental templates and atlases. The laboratory is closely linked to the TransMedTech institute and the Research Center of the Sainte-Justine University Hospital, enabling strong collaborations between researchers, engineers, psychologists, radiologists, and clinicians.

  • Medical imaging
  • Computer vision
  • Pediatric neuroimaging
  • Image processing and analysis
  • Machine learning
  • Modelisation
Expertise type(s) (NSERC subjects)
  • 1901 Biomedical technology
  • 2603 Computer vision
  • 2605 Pattern analysis and machine intelligence
  • 2604 Intelligent systems applications
  • 2708 Image and video processing


Recent publications
Journal article
Mangeat, G., Ouellette, R., Wabartha, M., De Leener, B., Platten, M., Karrenbauer, V.D., Warntjes, M., Stikov, N., Mainero, C., Cohen-Adad, J. & Granberg, T. (2020). Machine Learning and Multiparametric Brain MRI to Differentiate Hereditary Diffuse Leukodystrophy with Spheroids from Multiple Sclerosis. Journal of Neuroimaging, 30(5), 674-682. Retrieved from
Journal article
Gros, C., De Leener, B., Badji, A., Maranzano, J., Eden, D., Dupont, S.M., Talbott, J., Zhuoquiong, R., Liu, Y., Granberg, T., Ouellette, R., Tachibana, Y., Hori, M., Kamiya, K., Chougar, L., Stawiarz, L., Hillert, J., Bannier, E., Kerbrat, A., Edan, G., Labauge, P., Callot, V., Pelletier, J., Audoin, B., Rasoanandrianina, H., Brisset, J.-C., Valsasina, P., Rocca, M.A., Filippi, M., Bakshi, R., Tauhid, S., Prados, F., Yiannakas, M., Kearney, H., Ciccarelli, O., Smith, S., Treaba, C.A., Mainero, C., Lefeuvre, J., Reich, D.S., Nair, G., Auclair, V., McLaren, D.G., Martin, A.R., Fehlings, M.G., Vahdat, S., Khatibi, A., Doyon, J., Shepherd, T., Charlson, E., Narayanan, S. & Cohen-Adad, J. (2019). Automatic segmentation of the spinal cord and intramedullary multiple sclerosis lesions with convolutional neural networks. NeuroImage, 184, 901-915. Retrieved from
Conference paper
Ouellette, R., Treaba, C.A., Granberg, T., Herranz, E., Barletta, V., Mehndiratta, A., De Leener, B., Tauhid, S., Yousuf, F., Dupont, S., Klawiter, E.C., Sloane, J.A., Bakshi, R., Cohen-Adad, J. & Mainero, C. (2019). Characterization of outer and inner spinal cord pathology in multiple sclerosis by 7 Tesla imaging [Abstract]. Paper presented at the 35th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS) and 24th Annual Conference of Rehabilitation in MS, Stockholm, Sweden. (Published in Multiple Sclerosis Journal, 25, 681-682). Retrieved from
Conference paper
Shahrampour, S., De Leener, B., Middleton, D., Jonnavithula, K., Alizadeh, M., Pediyakkal, H., Krisa, L., Flanders, A., Faro, S., Cohen-Adad, J. & Mohamed, F. (2019). Development of a standardized normative pediatric spinal cord structural template : demonstration of an automatic estimation of spinal cord cross sectional area measurements (SCCSA). Paper presented at the ISMRM 27th Annual Meeting & Exhibition, Montréal, Qc.


INF1005D – Programmation procédurale en Python

INF1007 - Introduction à la programmation

GBM8770 - Traitement numérique d'images médicales


  • Ph.D. in biomedical engineering, Polytechnique Montréal, Canada
  • Master in biomedical engineering, Polytechnique Montréal, Canada
  • Master in biomedical engineering, Université Libre de Bruxelles, Belgium
  • Bachelor in civil engineering, Université Libre de Bruxelles, Belgium

Supervision at Polytechnique


  • Ph.D. (2)

    • Moevus, Antoine.
    • Zhang, Erjun.

Press review about Benjamin De Leener

March 10, 2020, McGill, Neural Pathways: Dr. Benjamin De Leener Article sur Benjamin De Leener, professeur adjoint au Département de génie informatique et génie logiciel de Polytechnique Montréal et titulaire de la chaire de recherche TransMedTech.