Séminaire sur les jeux dynamiques et les applications

Improving treatment of metastatic cancer through game theory

Katerina Stankova – Department of Data Science and Knowledge Engineering, Maastricht University, Pays-Bas

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In this talk, we will investigate cancer treatment as a game-theoretic contest between the physician's therapy and the cancer cells' resistance strategies. This game has two critical asymmetries: (1) Only the physician can play rationally. Cancer cells, like all evolving organisms, can only adapt to current conditions; they can neither anticipate nor evolve adaptations for treatments that the physician has not yet applied. (2) It has a distinctive Stackelberg structure; the "leader" oncologist plays first and the "follower" cancer cells then respond and adapt to therapy. We will learn how the physician can utilize his advantages in this game.