Description
Physical concepts nanotechnology and applications in the biomedical realm. Top-down and bottom-up approaches to nanotechnology. Synthesis and functionalization of metallic and semiconductor nanomaterials used in biomedical applications. Plasmonics: permittivity of metallic and alloy materials, the concept of volumic and surface plasmon, dipole approximation,hot spots, Mie theory, Calculation of optical cross sections. Optical biological nano-sensors: theory and application of plasmonics sensors, biosensors based on surface plasmon resonance (SPR), Surface Enhanced Raman Spectroscopy (SERS). Fluorescence resonance energy transfer (FRET). Plasmonic enhanced nanotherapy: nanophotothermy, hyperthermia, calculation of temperature increases, nanosurgery, therapeutic applications. Quantum dots: physics , spectroscopy and biological applications. Optical nanoparticles as contrast agents in optical Imaging, microscopy configuration. Biomedical nanomagnetism: properties of magnetic nanomaterials, hysteresis curve, superparamagnetism, applications in biodetection, contrast agent in magnetic resonance imaging and hyperthermia. Calculation of temperature increases. Other nanomaterials: Lipid nanoparticles and carbon Nanotubes and their applications in biology and medicine. Background in electromagnetism, optics, statistical physics, and quantum mechanics is preferable. Students can take either this course or GBM8810E, not both.