This multidisciplinary chair aims at determining the basic mechanisms governing the cellular response of growing bone tissue to
its mechanical environment in order to further exploit this knowledge for orthopaedic treatments of infants/adolescents in
clinics. It includes three complementary avenues of research: I) Experimental tissue and cell mechanics (to
characterize stress-strain relationships of growth plates, their cells and cellular components in response to loading);
II) Mechanotransduction (to establish in vivo the metabolic responses of growing bones to loading); and
III) Biomechanical modeling (to develop computer models to investigate the mechanical growth modulation and pathological
progressive deformities). In the long term, it is anticipated that these research projects will provide a scientific basis for
the orthopedic treatment of musculo-skeletal progressive deformities.
Research Personnel
Professors/Researchers: 1
Graduate Students: 6
Postdoctoral Fellows: 1
Research Assistants and Technicians: 1
Specialized Equipments
Inverted laser scanning confocal microscope combined with a 2-photon laser and a custom built loading apparatus, micro-testing
machine for soft tissues, wet lab with specialized apparatus for the preparation of soft/bone tissue samples.
