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Canada Research Chair in Mechanobiology of the Pediatric Musculoskeletal System

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Research Specification

This multidisciplinary chair aims at determining the basic mechanisms governing the cellular response of growing bone tissue to its mechanical environment in order to further exploit this knowledge for orthopaedic treatments of infants/adolescents in clinics.  It includes three complementary avenues of research: I) Experimental tissue and cell mechanics (to characterize stress-strain relationships of growth plates, their cells and cellular components in response to loading); II) Mechanotransduction (to establish in vivo the metabolic responses of growing bones to loading); and III) Biomechanical modeling (to develop computer models to investigate the mechanical growth modulation and pathological progressive deformities). In the long term, it is anticipated that these research projects will provide a scientific basis for the orthopedic treatment of musculo-skeletal progressive deformities.

Research Personnel

  • Professors/Researchers: 1
  • Graduate Students: 6
  • Postdoctoral Fellows: 1
  • Research Assistants and Technicians: 1

Specialized Equipments

Inverted laser scanning confocal microscope combined with a 2-photon laser and a custom built loading apparatus, micro-testing machine for soft tissues, wet lab with specialized apparatus for the preparation of soft/bone tissue samples.

External Sources of Funding



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