Directory of Experts

Lesage, Frédéric

Directory of Experts

Lesage, Frédéric

Directory of Experts

Publications by type

Journal article (193) Conference paper (109) Book Book chapter (2) Patent (2) Report Thesis Dataset Teaching resource Image Audio recording Video recording Other

Frédéric Lesage (306)

Journal articles (193)
- 2023
  - Bakker, M. E., Djerourou, I., Belanger, S., Lesage, F., & Vanni, M. P. (2023). Alteration of functional connectivity despite preserved cerebral oxygenation during acute hypoxia. Scientific Reports, 13(1), 16 pages.
  - Belgharbi, H., Poree, J., Damseh, R., Perrot, V., Milecki, L., Delafontaine-Martel, P., Lesage, F., & Provost, J. (2023). An Anatomically Realistic Simulation Framework for 3D Ultrasound Localization Microscopy. IEEE Open Journal of Ultrasonics, Ferroelectrics, and Frequency Control, 3, 1-13.
  - Gagliano, L., Ding, T. Y., Toffa, D. H., Beauregard, L., Robert, M., Lesage, F., Sawan, M., Nguyen, D. K., & Bou Assi, E. (2023). Decrease in wearable-based nocturnal sleep efficiency precedes epileptic seizures. Frontiers in Neurology, 13, 1089094 (11 pages).
  - Gagliano, L., Assi, E. B., Herrera-Fortin, T., Lesage, F., Sawan, M., & Nguyen, D. K. (2023). Epileptic Prodromes: Insights from Surveying 196 Patients and 150 Caregivers. Canadian Journal of Neurological Sciences, 50(1), 72-82.
  - Lemoine, É., Toffa, D., Pelletier-Mc Duff, G., Xu, A. Q., Jemel, M., Tessier, J.-D., Lesage, F., Nguyen, D. K., & Bou Assi, E. (2023). Machine-learning for the prediction of one-year seizure recurrence based on routine electroencephalography. Scientific Reports, 13(1), 13 pages.
  - Walek, K. W., Stefan, S., Lee, J.-H., Puttigampala, P., Kim, A. H., Park, S. W., Marchand, P. J., Lesage, F., Liu, T., Huang, Y.-W. A., Boas, D. A., Moore, C., & Lee, J. (2023). Near-lifespan longitudinal tracking of brain microvascular morphology, topology, and flow in male mice. Nature Communications, 14(1), 2982 (13 pages).
  - Langlais, É. L., Thériault-Lauzier, P., Marquis-Gravel, G., Kulbay, M., So, D. Y., Tanguay, J.-F., Ly, H. Q., Gallo, R., Lesage, F., & Avram, R. (2023). Novel Artificial Intelligence Applications in Cardiology: Current Landscape, Limitations, and the Road to Real-World Applications. Journal of Cardiovascular Translational Research, 16(3), 513-525.
  - Delafontaine-Martel, P., Zhang, C., Lu, X., Damseh, R., Lesage, F., & Marchand, P. J. (2023). Targeted capillary photothrombosis via multiphoton excitation of Rose Bengal. Journal of Cerebral Blood Flow & Metabolism, 43(10), 1713-1725.
- 2022
  - Trigiani, L. J., Bourourou, M., Lacalle-Aurioles, M., Lecrux, C., Hynes, A., Spring, S., Fernandes, D. J., Sled, J. G., Lesage, F., Schwaninger, M., & Hamel, E. (2022). A functional cerebral endothelium is necessary to protect against cognitive decline. Journal of Cerebral Blood Flow & Metabolism, 42(1), 74-89.
  - Labbé, P., Munoz Goyette, V., Thorin-Trescases, N., Villeneuve, L., Desanlis, I., Delwarde, C., Shi, Y.-F., Martel, C., Yu, C., Alikashani, A., Mamarbachi, M., Lesage, F., Mathieu, S., Tardif, J.-C., Mathieu, P., Kmita, M., & Thorin, É. (2022). Angiopoietin-like 2 is essential to aortic valve development in mice. Communications Biology, 5(1), 18 pages.
  - Corbin, D., & Lesage, F. (2022). Assessment of the predictive potential of cognitive scores from retinal images and retinal fundus metadata via deep learning using the CLSA database. Scientific Reports, 12(1), 12 pages.
  - Brun, O., Zoukimian, C., Oliveira-Mendes, B., Montnach, J., Lauzier, B., Ronjat, M., Béroud, R., Lesage, F., Boturyn, D., & De Waard, M. (2022). Chemical Synthesis of a Functional Fluorescent-Tagged α-Bungarotoxin. Toxins, 14(2), 18 pages.
  - Stefan, S., Kim, A., Marchand, P. J., Lesage, F., & Lee, J. (2022). Deep Learning and Simulation for the Estimation of Red Blood Cell Flux With Optical Coherence Tomography. Frontiers in Neuroscience, 16, 835773 (9 pages).
  - Talamonti, D., Gagnon, C., Vincent, T., Nigam, A., Lesage, F., Bherer, L., & Fraser, S. (2022). Exploring cognitive and brain oxygenation changes over a 1-year period in physically active individuals with mild cognitive impairment: a longitudinal fNIRS pilot study. BMC Geriatrics, 22(1), 13 pages.
  - Bourquin, C., Poree, J., Lesage, F., & Provost, J. (2022). In vivo pulsatility measurement of cerebral microcirculation in rodents using Dynamic Ultrasound Localization Microscopy. IEEE Transactions on Medical Imaging, 41(4), 782-792.
  - Wang, Y.-C., Théberge-Julien, G., Tardif, J.-C., Rhéaume, É., Lesage, F., & Kakkar, A. (2022). Multifaceted ligand design facilitates chemical- or peptide-mediated linking of hollow gold nanoshells with tuned interparticle distance, interference and cytotoxicities. Materials advances, 3(19), 7272-7284.
  - Sirpal, P., Damseh, R., Peng, K., Nguyen, D. K., & Lesage, F. (2022). Multimodal autoencoder predicts fNIRS resting state from EEG signals. Neuroinformatics, 2021(3), 537-558.
  - Pierre, W. C., Zhang, E., Londono, I., De Leener, B., Lesage, F., & Lodygensky, G. A. (2022). Non-invasive in vivo MRI detects long-term microstructural brain alterations related to learning and memory impairments in a model of inflammation-induced white matter injury. Behavioural Brain Research, 428, 113884 (13 pages).
  - Talamonti, D., Dupuy, E. G., Boudaa, S., Vincent, T., Fraser, S., Nigam, A., Lesage, F., Belleville, S., Gagnon, C., & Bherer, L. (2022). Prefrontal hyperactivation during dual-task walking related to apathy symptoms in older individuals. PLOS ONE, 17(4), 13 pages.
  - Koffi, N. G. M., Eftimov, T. A., Arapova, A., Lesage, F., Bock, W. J., & Cherif, A. (2022). Simultaneous measurement of thermal gradient and average temperature in concrete blocks using nonuniform long-period optical fiber gratings. IEEE Transactions on Instrumentation and Measurement, 71, 1-8.
- 2021
  - Milecki, L., Porée, J., Belgharbi, H., Bourquin, C., Damseh, R., Delafontaine-Martel, P., Lesage, F., Gasse, M., & Provost, J. (2021). A deep learning framework for spatiotemporal ultrasound localization microscopy. IEEE Transactions on Medical Imaging, 40(5), 1428-1437.
  - Trigiani, L. J., Lecrux, C., Royea, J., Lavoie, J. L., Lesage, F., Pilote, L., & Hamel, E. (2021). A Longitudinal Pilot Study on Cognition and Cerebral Hemodynamics in a Mouse Model of Preeclampsia Superimposed on Hypertension: Looking at Mothers and Their Offspring. Frontiers in Physiology, 12, 611984 (9 pages).
  - Tahir, W., Kura, S., Zhu, J., Cheng, X., Damseh, R., Tadesse, F., Seibel, A., Lee, B. S., Lesage, F., Sakadzic, S., Boas, D. A., & Tian, L. (2021). Anatomical Modeling of Brain Vasculature in Two-Photon Microscopy by Generalizable Deep Learning. BME Frontiers, 2021, 8620932 (12 pages).
  - Damseh, R., Lu, Y., Lu, X., Zhang, C., Marchand, P. J., Corbin, D., Pouliot, P., Cheriet, F., & Lesage, F. (2021). A simulation study investigating potential diffusion-based MRI signatures of microstrokes. Scientific Reports, 11(1), 14229 (15 pages).
  - Yucel, M. A., Luhmann, A. V., Scholkmann, F., Gervain, J., Dan, I., Ayaz, H., Boas, D., Cooper, R. J., Culver, J., Elwell, C. E., Eggebrecht, A., Franceschini, M. A., Grova, C., Homae, F., Lesage, F., Obrig, H., Tachtsidis, I., Tak, S., Tong, Y., ... Wolf, M. (2021). Best practices for fNIRS publications. Neurophotonics, 8(1), 34 pages.
  - Mohammadi, H., Vincent, T., Peng, K., Nigam, A., Gayda, M., Fraser, S., Joanette, Y., Lesage, F., & Bherer, L. (2021). Coronary artery disease and its impact on the pulsatile brain: A functional NIRS study. Human Brain Mapping, 42(12), 3760-3776.
  - Mohammadi, H., Peng, K., Kassab, A., Nigam, A., Bherer, L., Lesage, F., & Joanette, Y. (2021). Cortical Thinning is Associated with Brain Pulsatility in Older Adults: An MRI and NIRS Study. Neurobiology of Aging, 106, 103-118.
  - Yucel, M. A., Luhmann, A. V., Scholkmann, F., Gervain, J., Dan, I., Ayaz, H., Boas, D., Cooper, R. J., Culver, J., Elwell, C. E., Eggebrecht, A., Franceschini, M. A., Grova, C., Homae, F., Lesage, F., Obrig, H., Tachtsidis, I., Tak, S., Tong, Y., ... Wolf, M. (2021). Erratum: Best practices for fNIRS publications. Neurophotonics, 8(1), 2 pages.
  - Kassab, A., Toffa, D. H., Robert, M., Lesage, F., Peng, K., & Nguyen, D. K. (2021). Hemodynamic changes associated with common EEG patterns in critically ill patients: Pilot results from continuous EEG-fNIRS study. Neuroimage-Clinical, 32, 102880 (18 pages).
  - Shokooh, L. A., Toffa, D. H., Pouliot, P., Lesage, F., & Nguyen, D. K. (2021). Intracranial EEG seizure onset and termination patterns and their association. Epilepsy Research, 176, 106739 (8 pages).
  - Damseh, R., Delafontaine-Martel, P., Pouliot, P., Cheriet, F., & Lesage, F. (2021). Laplacian Flow Dynamics on Geometric Graphs for Anatomical Modeling of Cerebrovascular Networks. IEEE Transactions on Medical Imaging, 40(1), 381-394.
  - Mohammadi, H., Gagnon, C., Vincent, T., Kassab, A., Fraser, S., Nigam, A., Lesage, F., & Bherer, L. (2021). Longitudinal Impact of Physical Activity on Brain Pulsatility Index and Cognition in Older Adults with Cardiovascular Risk Factors: A NIRS Study. Brain Sciences, 11(6), 14 pages.
  - Hardy, E., Porée, J., Belgharbi, H., Bourquin, C., Lesage, F., & Provost, J. (2021). Sparse channel sampling for ultrasound localization microscopy (SPARSE-ULM). Physics in Medicine & Biology, 66(9), 095008.
  - Talamonti, D., Vincent, T., Fraser, S., Nigam, A., Lesage, F., & Bherer, L. (2021). The benefits of physical activity in individuals with cardiovascular risk factors : a longitudinal investigation using fNIRS and dual-task walking. Journal of Clinical Medicine, 10(4), 579 (14 pages).
  - Hartung, G., Badr, S., Moeini Gharagozlo, M. R., Lesage, F., Kleinfeld, D., Alaraj, A., & Linninger, A. (2021). Voxelized simulation of cerebral oxygen perfusion elucidates hypoxia in aged mouse cortex. PLOS Computational Biology, 17(1), e1008584 (28 pages).
- 2020
  - Langeard, A., Saillant, K., Charlebois Cloutier, E., Gayda, M., Lesage, F., Nigam, A., Bherer, L., & Fraser, S. A. (2020). Association between Statin Use and Balance in Older Adults. International Journal of Environmental Research and Public Health, 17(13), 4662 (9 pages).
  - Moeini, M., Cloutier-Tremblay, C., Lu, X., Kakkar, A., & Lesage, F. (2020). Cerebral tissue pO2 response to treadmill exercise in awake mice. Scientific Reports, 10(1), 13358 (11 pages).
  - Saha, S., Lu, Y., Weyers, S., Lesage, F., & Sawan, M. (2020). Compact Optical Probe for Time-Resolved NIRS-Imaging. IEEE Sensors Journal, 20(11), 6101-6113.
  - Soucy, J.‐.P., Chevrefils, C., Osseiran, S., Sylvestre, J.‐.P., Beaulieu, S., Pascoal, T. A., Arbour, J. D., Rhéaume, M.‐.A., Villeneuve, S., Nasreddine, Z. S., Rosa‐Neto, P., Gauthier, S., Robillard, A., Chayer, C., Black, S. E., Kertes, P. J., Shahawy, H. E., Chen, J. J., Knopman, D. S., ... Lesage, F. (2020). Evaluation of a retinal deep phenotyping platform to detect the likely cerebral amyloid PET status in humans. Alzheimer's & Dementia, 16(S4).
  - Lu, X., Moeini, M., Li, B., Thorin, E., & Lesage, F. (2020). Hypertension accelerates cerebral tissue PO₂ disruption in Alzheimer's disease. Neuroscience Letters, 715, 134626 (7 pages).
  - Abrishami Shokooh, L., Toffa, D. H., Pouliot, P., Lesage, F., & Nguyen, D. K. (2020). Identification of global and local states during seizures using quantitative functional connectivity and recurrence plot analysis. Computers in Biology and Medicine, 122, 11 pages.
  - Assi, E. B., Zerouali, Y., Robert, M., Lesage, F., Pouliot, P., & Nguyen, D. K. (2020). Large-Scale Desynchronization During Interictal Epileptic Discharges Recorded With Intracranial EEG. Frontiers in Neurology, 11, 529460 (12 pages).
  - Lu, Y., Lu, X., Zhang, C., Marchand, P. J., & Lesage, F. (2020). Longitudinal optical coherence tomography imaging of tissue repair and microvasculature regeneration and function after targeted cerebral ischemia. Journal of Biomedical Optics, 25(4), 15 pages.
  - Guevara, E., Flores-Castro, J.-A., Peng, K., Nguyen, D. K., Lesage, F., Pouliot, P., & Rosas-Romero, R. (2020). Prediction of epileptic seizures using fNIRS and machine learning. Journal of Intelligent & Fuzzy Systems, 38(2), 2055-2068.
  - Dallaire, F., Picot, F., Tremblay, J.-P., Sheehy, G., Lemoine, É., Agarwal, R., Kadoury, S., Trudel, D., Lesage, F., Petrecca, K., & Leblond, F. (2020). Quantitative spectral quality assessment technique validated using intraoperative in vivo Raman spectroscopy measurements. Journal of Biomedical Optics, 25(4).
  - Marchand, P. J., Lu, X., Zhang, C., & Lesage, F. (2020). Validation of red blood cell flux and velocity estimations based on optical coherence tomography intensity fluctuations. Scientific Reports, 10(1), 19584 (10 pages).
  - Lu, X., Moeini, M., Li, B., de Montgolfier, O., Lu, Y., Belanger, S., Thorin, E., & Lesage, F. (2020). Voluntary exercise increases brain tissue oxygenation and spatially homogenizes oxygen delivery in a mouse model of Alzheimer's disease. Neurobiology of Aging, 88, 11-23.
- 2019
  - Lu, X., Moeini, M., Li, B., Lu, Y., Damseh, R., Pouliot, P., Thorin, E., & Lesage, F. (2019). A Pilot Study Investigating Changes in Capillary Hemodynamics and Its Modulation by Exercise in the APP-PS1 Alzheimer Mouse Model. Frontiers in Neuroscience, 13, 1261 (12 pages).
  - Lefebvre, J., Delafontaine-Martel, P., & Lesage, F. (2019). A review of intrinsic optical imaging serial blockface histology (ICI-SBH) for whole rodent brain imaging. Photonics, 6(2), 66 (27 pages).
  - Pierre, W. C., Akakpo, L., Londono, I., Pouliot, P., Chemtob, S., Lesage, F., & Lodygensky, G. A. (2019). Assessing therapeutic response non-invasively in a neonatal rat model of acute inflammatory white matter injury using high-field MRI. Brain, Behavior, and Immunity, 81, 348-360.
  - Zhang, C., Tabatabaei, M., Belanger, S., Girouard, H., Moeini, M., Lu, X., & Lesage, F. (2019). Astrocytic endfoot Ca2+ correlates with parenchymal vessel responses during 4-AP induced epilepsy: An in vivo two-photon lifetime microscopy study. Journal of Cerebral Blood Flow & Metabolism, 39(2), 260-271.
  - Li, B., Lu, X., Moeini, M., Sakadzic, S., Thorin, E., & Lesage, F. (2019). Atherosclerosis is associated with a decrease in cerebral microvascular blood flow and tissue oxygenation. PLOS One, 14(8), e0221547 (13 pages).
  - Damseh, R., Pouliot, P., Gagnon, L., Sakadzic, S., Boas, D., Cheriet, F., & Lesage, F. (2019). Automatic Graph-based Modeling of Brain Microvessels Captured with Two-Photon Microscopy. IEEE Journal of Biomedical and Health Informatics, 23(6), 2551-2562.
  - Moeini, M., Lu, X., Belanger, S., Picard, F., Boas, D., Kakkar, A., & Lesage, F. (2019). Cerebral tissue pO₂ response to stimulation is preserved with age in awake mice. Neuroscience Letters, 699, 160-166.
  - Sirpal, P., Kassab, A., Pouliot, P., Nguyen, D. K., & Lesage, F. (2019). fNIRS improves seizure detection in multimodal EEG-fNIRS recordings. Journal of Biomedical Optics, 24(5), 051408 (9 pages).
  - de Montgolfier, O., Pincon, A., Pouliot, P., Gillis, M.-A., Bishop, J., Sled, J. G., Villeneuve, L., Ferland, G., Levy, B. I., Lesage, F., Thorin-Trescases, N., & Thorin, E. (2019). High systolic blood pressure induces cerebral microvascular endothelial dysfunction, neurovascular unit damage, and cognitive decline in mice. Hypertension, 73(1), 217-228.
  - Lu, Y., Zhang, C., Lu, X., Moeini, M., Thorin, E., & Lesage, F. (2019). Impact of atherosclerotic disease on cerebral microvasculature and tissue oxygenation in awake LDLR-/-hApoB+/+ transgenic mice. Neurophotonics, 6(4), 045003 (10 pages).
  - Pinto, M., Zorn, K. C., Tremblay, J.-P., Desroches, J., Dallaire, F., Aubertin, K., Marple, E., Kent, C., Leblond, F., Trudel, D., & Lesage, F. (2019). Integration of a Raman spectroscopy system to a robotic-assisted surgical system for real-time tissue characterization during radical prostatectomy procedures. Journal of Biomedical Optics, 24(2), 025001 (10 pages).
  - Bertrand, M.-J., Abran, M., Maafi, F., Busseuil, D., Merlet, N., Mihalache-Avram, T., Geoffroy, P., Tardif, P.-L., Abulrob, A., Arbabi-Ghahroudi, M., Ni, F., Sirois, M., L'Allier, P. L., Rhéaume, É., Lesage, F., & Tardif, J.-C. (2019). In vivo near-infrared fluorescence imaging of atherosclerosis using local delivery of novel targeted molecular probes. Scientific Reports, 9(1).
  - Koffi, N. , Eftimov, T. A., Lesage, F., Mikulic, P., & Bock, W. J. (2019). Measurement of thermal gradients using long period gratings at different levels of ambient refractive indices. Journal of Lightwave Technology, 37(18), 4674-4679.
  - Li, B., Esipova, T. V., Sencan, I., Kilic, K., Fu, B., Desjardins, M., Moeini, M., Kura, S., Yaseen, M. A., Lesage, F., Ostergaard, L., Devor, A., Boas, D. A., Vinogradov, S. A., & Sakadzic, S. (2019). More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction. eLife, 8, e42299 (28 pages).
  - Pinçon, A., De Montgolfier, O., Akkoyunlu, N., Daneault, C., Pouliot, P., Villeneuve, L., Lesage, F., Levy, B. I., Thorin-Trescases, N., Thorin, É., & Ruiz, M. (2019). Non-alcoholic fatty liver disease, and the underlying altered fatty acid metabolism, reveals brain hypoperfusion and contributes to the cognitive decline in APP/PS1 mice. Metabolites, 9(5), 20 pages.
  - Hadoux, X., Hui, F., Lim, J. K. H., Masters, C. L., Pébay, A., Chevalier, S., Ha, J., Loi, S., Fowler, C. J., Rowe, C., Villemagne, V. L., Taylor, E. N., Fluke, C., Soucy, J.-P., Lesage, F., Sylvestre, J.-P., Rosa-Neto, P., Mathotaarachchi, S., Gauthier, S., ... van Wijngaarden, P. (2019). Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer's disease. Nature Communications, 10(1), 4227 (12 pages).
  - Rosas-Romero, R., Guevara, E., Peng, K., Nguyen, D. K., Lesage, F., Pouliot, P., & Lima-Saad, W.-E. (2019). Prediction of epileptic seizures with convolutional neural networks and functional near-infrared spectroscopy signals. Computers in Biology and Medicine, 111, 10 pages.
  - Langeard, A., Saillant, K., Cloutier, E. C., Gayda, M., Lesage, F., Nigam, A., Bherer, L., & Fraser, S. (2019). Statin use is associated with poorer static balance performance in older adults. Neurophysiologie Clinique-clinical Neurophysiology, 413-413.
  - de Montgolfier, O., Pouliot, P., Gillis, M.-A., Ferland, G., Lesage, F., Thorin-Trescases, N., & Thorin, E. (2019). Systolic hypertension-induced neurovascular unit disruption magnifies vascular cognitive impairment in middle-age atherosclerotic LDLr-/-:hApoB(+/+) mice. Geroscience, 41(5), 511-532.
  - Sharafi, S. M., Sylvestre, J.‐.P., Chevrefils, C., Soucy, J.‐.P., Beaulieu, S., Pascoal, T. A., Arbour, J. D., Rhéaume, M.‐.A., Robillard, A., Chayer, C., Rosa‐Neto, P., Mathotaarachchi, S. S., Nasreddine, Z. S., Gauthier, S., & Lesage, F. (2019). Vascular retinal biomarkers improves the detection of the likely cerebral amyloid status from hyperspectral retinal images. Alzheimer's & Dementia: Translational Research & Clinical Interventions, 5(1), 610-617.
  - Saha, S., Lu, Y., Lesage, F., & Sawan, M. (2019). Wearable SiPM-based NIRS Interface Integrated with Pulsed Laser Source. IEEE Transactions on Biomedical Circuits and Systems, 13(6), 1313-1323.
- 2018
  - Saha, S., Lu, Y., Weyers, S., Sawan, M., & Lesage, F. (2018). Compact Fast Optode-based Probe for Single-Photon Counting Applications. IEEE Photonics Technology Letters, 30(17), 1515-1518.
  - Castonguay, A., Lefebvre, J., Pouliot, P., & Lesage, F. (2018). Comparing three-dimensional serial optical coherence tomography histology to MRI imaging in the entire mouse brain. Journal of Biomedical Optics, 23(1), 9 pages.
  - Moeini, M., Lu, X., Avti, P. K., Damseh, R., Bélanger, S., Picard, F., Boas, D., Kakkar, A., & Lesage, F. (2018). Compromised microvascular oxygen delivery increases brain tissue vulnerability with age. Scientific Reports, 8(1), 8219 (17 pages).
  - Lopez Rios, N., Pouliot, P., Papoutsis, K., Foias, A., Stikov, N., Lesage, F., Dehaes, M., & Cohen-Adad, J. (2018). Design and construction of an optimized transmit/receive hybrid birdcage resonator to improve full body images of medium-sized animals in 7T scanner. PLOS One, 13(2), e0192035 (14 pages).
  - Lefebvre, J., Delafontaine-Martel, P., Pouliot, P., Girouard, H., Descoteaux, M., & Lesage, F. (2018). Fully automated dual-resolution serial optical coherence tomography aimed at diffusion MRI validation in whole mouse brains. Neurophotonics, 5(4), 045004 (16 pages).
  - Soucy, J.-P., Chevrefils, C., Sylvestre, J.-P., Arbour, J. D., Rhéaume, M.-A., Beaulieu, S., Chayer, C., Robillard, A., Rosa-Neto, P., Mathotaarachchi, S., Nasreddine, Z. S., Gauthier, S., & Lesage, F. (2018). IC‐P‐190: An amyloid ligand‐free optical retinal imaging method to predict cerebral amyloid pet status. Alzheimer's & Dementia, 14(7S_Part_2).
  - Kassab, A., Le Lan, J., Tremblay, J., Vannasing, P., Dehbozorgi, M., Pouliot, P., Gallagher, A., Lesage, F., Sawan, M., & Nguyen, D. K. (2018). Multichannel wearable fNIRS-EEG system for long-term clinical monitoring. Human Brain Mapping, 39(1), 7-23.
  - Soucy, J.-P., Chevrefils, C., Sylvestre, J.-P., Arbour, J. D., Rhéaume, M.-A., Beaulieu, S., Chayer, C., Robillard, A., Rosa-Neto, P., Mathotaarachchi, S., Nasreddine, Z. S., Gauthier, S., & Lesage, F. (2018). P2‐252: An amyloid ligand‐free optical retinal imaging method to predict cerebral amyloid pet status. Alzheimer's & Dementia, 14(7S_Part_14).
  - Alameh, M., Lavertu, M., Tran-Khanh, N., Chang, C. Y., Lesage, F., Bail, M., Darras, V., Chevrier, A., & Buschmann, M. D. (2018). siRNA delivery with chitosan: influence of chitosan molecular weight, degree of deacetylation, and amine to phosphate ratio on in vitro silencing efficiency, hemocompatibility, biodistribution, and in vivo efficacy. Biomacromolecules, 19(1), 112-131.
  - Wang, Y.-C., Rheaume, É., Lesage, F., & Kakkar, A. (2018). Synthetic methodologies to gold nanoshells: An overview. Molecules, 23(11).
  - Delafontaine-Martel, P., Lefebvre, J., Tardif, P.-L., Lévy, B. I., Pouliot, P., & Lesage, F. (2018). Whole brain vascular imaging in a mouse model of Alzheimer's disease with two-photon microscopy. Journal of Biomedical Optics, 23(7), 10 pages.
- 2017
  - Guevara, E., Pierre, W. C., Tessier, C., Akakpo, L., Londono, I., Lesage, F., & Lodygensky, G. A. (2017). Altered functional connectivity following an inflammatory white matter injury in the newborn rat: A high spatial and temporal resolution intrinsic optical imaging study. Frontiers in Neuroscience, 11, 358 (11 pages).
  - Naderian, A., Bussieres, L., Thomas, S., Lesage, F., & Casanova, C. (2017). Cellular origin of intrinsic optical signals in the rabbit retina. Vision Research, 137, 40-49.
  - Maafi, F., Li, B., Gebhard, C., Brodeur, M. R., Nachar, W., Villeneuve, L., Lesage, F., Rhainds, D., Rhéaume, E., & Tardif, J.-C. (2017). Development of a new bioactivatable fluorescent probe for quantification of apolipoprotein A-I proteolytic degradation in vitro and in vivo. Atherosclerosis, 258, 8-19.
  - Pouliot, P., Gagnon, L., Lam, T., Avti, P. K., Bowen, C., Desjardins, M., Kakkar, A. K., Thorin, E., Sakadzic, S., Boas, D. A., & Lesage, F. (2017). Magnetic resonance fingerprinting based on realistic vasculature in mice. NeuroImage, 149, 436-445.
  - Guevara, E., Manuel Gutierrez-Hernandez, J., Castonguay, A., Lesage, F., Moncada, B., & Javier Gonzalez, F. (2017). Morphological and molecular imaging of skin samples. Biomedical Research-India, 28(4), 1664-1669.
  - Raignault, A., Bolduc, V., Lesage, F., & Thorin, E. (2017). Pulse pressure-dependent cerebrovascular eNOS regulation in mice. Journal of Cerebral Blood Flow & Metabolism, 37(2), 413-424.
  - Castonguay, A., Lefebvre, J., Pouliot, P., Avti, P., Moeini, M., & Lesage, F. (2017). Serial optical coherence scanning reveals an association between cardiac function and the heart architecture in the aging rodent heart. Biomedical Optics Express, 8(11), 5027-5038.
  - Zhang, C., Moeini, M., & Lesage, F. (2017). Spatial landscape of oxygen in and around microvasculature during epileptic events. Neurophotonics, 4(1).
  - Lefebvre, J., Castonguay, A., Pouliot, P., Descoteaux, M., & Lesage, F. (2017). Whole mouse brain imaging using optical coherence tomography: reconstruction, normalization, segmentation, and comparison with diffusion MRI. Neurophotonics, 4(4), 041501 (14 pages).
- 2016
  - Fraser, S. A., Dupuy, O., Pouliot, P., Lesage, F., & Bherer, L. (2016). Comparable cerebral oxygenation patterns in younger and older adults during dual-task walking with increasing load. Frontiers in Aging Neuroscience, 8, 1-9.
  - Li, B., Lee, J., Boas, D. A., & Lesage, F. (2016). Contribution of low- and high-flux capillaries to slow hemodynamic fluctuations in the cerebral cortex of mice. Journal of Cerebral Blood Flow & Metabolism, 36(8), 1351-1356.
  - Belanger, S., Oliveira Ferreira de Souza, B., Casanova, C., & Lesage, F. (2016). Correlation of hemodynamic and fluorescence signals under resting state conditions in mice's barrel field cortex. Neuroscience Letters, 616, 177-181.
  - Lam, T., Avti, P. K., Pouliot, P., Maafi, F., Tardif, J.-C., Rhéaume, É., Lesage, F., & Kakkar, A. (2016). Fabricating water dispersible superparamagnetic iron oxide nanoparticles for biomedical applications through ligand exchange and direct conjugation. Nanomaterials, 6(6), 1-15.
  - Grasland-Mongrain, P., Yuankang, L., Lesage, F., Catheline, S., & Cloutier, G. (2016). Generation of shear waves by laser in soft media in the ablative and thermoelastic regimes. Applied Physics Letters, 109(22), 5 pages.
  - Pichette, J., Laurence, A., Angulo, L., Lesage, F., Bouthillier, A., Nguyen, D. K., & Leblond, F. (2016). Intraoperative video-rate hemodynamic response assessment in human cortex using snapshot hyperspectral optical imaging. Neurophotonics, 3(4).
  - Lam, T., Avti, P. K., Pouliot, P., Tardif, J.-C., Rheaume, E., Lesage, F., & Kakkar, A. (2016). Magnetic resonance imaging/fluorescence dual modality protocol using designed phosphonate ligands coupled to superparamagnetic iron oxide nanoparticles. Journal of Materials Chemistry B, 4(22), 3969-3981.
  - Zerouali, Y., Pouliot, P., Robert, M., Mohamed, I., Bouthillier, A., Lesage, F., & Nguyen, D. K. (2016). Magnetoencephalographic signatures of insular epileptic spikes based on functional connectivity. Human Brain Mapping, 37(9), 3250-3261.
  - Peng, K., Pouliot, P., Lesage, F., & Nguyen, D. K. (2016). Multichannel continuous electroencephalography-functional near-infrared spectroscopy recording of focal seizures and interictal epileptiform discharges in human epilepsy: A review. Neurophotonics, 3(3), 12 pages.
  - Castonguay, A., Thomas, S., Lesage, F., & Casanova, C. (2016). Optogenetic Tools for Confined Stimulation in Deep Brain Structures. Methods in Molecular Biology, 1408, 267-279.
  - Desjardins, M., Sylvestre, J. P., Jafari, R., Kulasekara, S., Rose, K., Trussart, R., Arbour, J. D., Hudson, C., & Lesage, F. (2016). Preliminary investigation of multispectral retinal tissue oximetry mapping using a hyperspectral retinal camera. Experimental Eye Research, 146, 330-340.
  - Auger, H., Bherer, L., Boucher, É., Hoge, R., Lesage, F., & Dehaes, M. (2016). Quantification of extra-cerebral and cerebral hemoglobin concentrations during physical exercise using time-domain near infrared spectroscopy. Biomedical Optics Express, 7(10), 3826-3842.
  - Lam, T., Avti, P. K., Pouliot, P., Tardif, J. C., Rheaume, E., Lesage, F., & Kakkar, A. (2016). Surface engineering of SPIONs: role of phosphonate ligand multivalency in tailoring their efficacy. Nanotechnology, 27(41), 11 pages.
  - Fraser, S., Vincent, T., Charlebois-Cloutier, E., Dupuy, O., Lesage, F., Nigam, A., & Bherer, L. (2016). Tracking cerebral activity of older adults with or without cardiovascular risk factors using FNIRS. The Gerontologist, 56(Suppl_3), 740-740.
  - Peng, K., Nguyen, D. K., Vannasing, P., Tremblay, J., Lesage, F., & Pouliot, P. (2016). Using patient-specific hemodynamic response function in epileptic spike analysis of human epilepsy: a study based on EEG-fNIRS. NeuroImage, 126, 239-255.
  - Tardif, P.-L., Bertrand, M.-J., Abran, M., Castonguay, A., Lefebvre, J., Stähli, B. E., Merlet, N., Mihalache-Avram, T., Geoffroy, P., Mecteau, M., Busseuil, D., Ni, F., Abulrob, A., Rhéaume, É., L’Allier, P., Tardif, J.-C., & Lesage, F. (2016). Validating intravascular imaging with serial optical coherence tomography and confocal fluorescence microscopy. International Journal of Molecular Sciences, 17(12), 1-12.
  - Gagnon, L., Sakadzic, S., Lesage, F., Pouliot, P., Dale, A. M., Devor, A., Buxton, R. B., & Boas, D. A. (2016). Validation and optimization of hypercapnic-calibrated fMRI from oxygen-sensitive two-photon microscopy. Philosophical Transactions of the Royal Society B-Biological Sciences, 371(1705), 13 pages.
- 2015
  - Kamrani, E., Lesage, F., & Sawan, M. (2015). A Low-Power Photon-Counter Front-End Dedicated to NIRS Brain Imaging. IEEE Sensors Journal, 15(7), 3724-3733.
  - Belanger-Nelson, E., Freyburger, M., Pouliot, P., Beaumont, E., Lesage, F., & Mongrain, V. (2015). Brain hemodynamic response to somatosensory stimulation in neuroligin-1 knockout mice. Neuroscience, 289, 242-250.
  - Bdard, M., Avti, P. K., Lam, T., Rouleau, L., Tardif, J.-C., Rhaume, E., Lesage, F., & Kakkar, A. (2015). Conjugation of multivalent ligands to gold nanoshells and designing a dual modality imaging probe. Journal of Materials Chemistry B, 3(9), 1788-1800.
  - Gauthier, C. J., Lefort, M., Mekary, S., Desjardins-Crepeau, L., Skimminge, A., Iversen, P., Madjar, C., Desjardins, M., Lesage, F., Garde, E., Frouin, F., Bherer, L., & Hoge, R. D. (2015). Hearts and minds: linking vascular rigidity and aerobic fitness with cognitive aging. Neurobiology of Aging, 36(1), 304-314.
  - Dupuy, O., Gauthier, C. J., Fraser, S. A., Desjardins-Crépeau, L., Desjardins, M., Mekary, S., Lesage, F., Hoge, R. D., Pouliot, P., & Bherer, L. (2015). Higher levels of cardiovascular fitness are associated with better executive function and prefrontal oxygenation in younger and older women. Frontiers in Human Neuroscience, 9.
  - Sakadzic, S., Mandeville, E., Gagnon, L., Musacchia, J., Yaseen, M., Yucel, M., Lefebvre, J., Lesage, F., Dale, A., Eikermann-Haerter, K., Ayata, C., Srinivasan, V., Lo, E., Devor, A., & Boas, D. (2015). Large Arteriolar Component of Oxygen Delivery Implies Safe Margin of Oxygen Supply to Cerebral Tissue. Faseb Journal, 29(1S), 1 page.
  - Zhang, C., Bélanger, S., Pouliot, P., & Lesage, F. (2015). Measurement of Local Partial Pressure of Oxygen in the Brain Tissue under Normoxia and Epilepsy with Phosphorescence Lifetime Microscopy. PLOS One, 10(8).
  - Lesage, F., & Obrig, H. (2015). Montréal SfNIRS conference shines light on the brain. Neurophotonics, 2(2), 020401 (2 pages).
  - Gagnon, L., Sakadzic, S., Lesage, F., Mandeville, E. T., Fang, Q. Q., Yaseen, M. A., & Boas, D. A. (2015). Multimodal reconstruction of microvascular-flow distributions using combined two-photon microscopy and Doppler optical coherence tomography. Neurophotonics, 2(1), 8 pages.
  - Hatef, A., Fortin-Deschnes, S., Boulais, É., Lesage, F., & Meunier, M. (2015). Photothermal response of hollow gold nanoshell to laser irradiation: Continuous wave, short and ultrashort pulse. International Journal of Heat and Mass Transfer, 89, 866-871.
  - Raignault, A., Bolduc, V., Lesage, F., & Thorin, E. (2015). Pulse Pressure Reveals Shear Stress-Dependent eNOS Activity in Mice Cerebral Arteries. Faseb Journal, 29(1S), 2 pages.
  - Gagnon, L., Sakadzic, S., Lesage, F., Musacchia, J. J., Lefebvre, J., Fang, Q. Q., Yucel, M. A., Evans, K. C., Mandeville, E. T., Cohen-Adad, J., Polimeni, J. R., Yaseen, M. A., Lo, E. H., Greve, D. N., Buxton, R. B., Dale, A. M., Devor, A., & Boas, D. A. (2015). Quantifying the Microvascular Origin of BOLD-fMRI from First Principles with Two-Photon Microscopy and an Oxygen-Sensitive Nanoprobe. Journal of Neuroscience, 35(8), 3663-3675.
  - Lague-Beauvais, M., Fraser, S. A., Desjardins-Crepeau, L., Castonguay, N., Desjardins, M., Lesage, F., & Bherer, L. (2015). Shedding light on the effect of priority instructions during dual-task performance in younger and older adults: A fNIRS study. Brain and Cognition, 98, 1-14.
  - Mekari, S., Fraser, S., Bosquet, L., Bonnery, C., Labelle, V., Pouliot, P., Lesage, F., & Bherer, L. (2015). The relationship between exercise intensity, cerebral oxygenation and cognitive performance in young adults. European Journal of Applied Physiology, 115(10), 2189-2197.
  - Abran, M., Stahli, B. E., Merlet, N., Mihalache-Avram, T., Mecteau, M., Rheaume, E., Busseuil, D., Tardif, J. C., & Lesage, F. (2015). Validating a bimodal intravascular ultrasound (IVUS) and near-infrared fluorescence (NIRF) catheter for atherosclerotic plaque detection in rabbits. Biomedical Optics Express, 6(10), 3989-3999.
  - Kulasekara, S., Rose, K., Desjardins, M., Jafari, R., Arbour, J. D., Lesage, F., Sylvestre, J.-P., & Hudson, C. (2015). Validation of model based hyperspectral retinal oximetry algorithms using systemic gas provocations in healthy individuals. Investigative Ophthalmology & Visual Science, 56(7), 3 pages.
- 2014
  - Desjardins, M., Berti, R., Lefebvre, J., Dubeau, S., & Lesage, F. (2014). Aging-related differences in cerebral capillary blood flow in anesthetized rats. Neurobiology of Aging, 35(8), 1947-1955.
  - Amiri, M., Pouliot, P., Bonnéry, C., Leclerc, P.-O., Desjardins, M., Lesage, F., & Joanette, Y. (2014). An exploration of the effect of hemodynamic changes due to normal aging on the fNIRS response to semantic processing of words. Frontiers in Neurology, 5.
  - Spinelli, L., Botwicz, M., Zolek, N., Kacprzak, M., Milej, D., Sawosz, P., Liebert, A., Weigel, U., Durduran, T., Foschum, F., Kienle, A., Baribeau, F., Leclair, S., Bouchard, J.-P., Noiseux, I., Gallant, P., Mermut, O., Farina, A., Pifferi, A., ... Zaccanti, G. (2014). Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink. Biomedical Optics Express, 5(7), 2037-2053.
  - Abran, M., Cloutier, G., Cardinal, M.-H. R., Chayer, B., Tardif, J.-C., & Lesage, F. (2014). Development of a Photoacoustic, Ultrasound and Fluorescence Imaging Catheter for the Study of Atherosclerotic Plaque. IEEE Transactions on Biomedical Circuits and Systems, 8(5), 696-703.
  - Peng, K., Nguyen, D. K., Tayah, T., Vannasing, P., Tremblay, J., Sawan, M., Lassonde, M., Lesage, F., & Pouliot, P. (2014). fNIRS-EEG study of focal interictal epileptiform discharges. Epilepsy Research, 108(3), 491-505.
  - Beaumont, E., Guevara, E., Dubeau, S., Lesage, F., Nagai, M., & Popovic, M. (2014). Functional electrical stimulation post-spinal cord injury improves locomotion and increases afferent input into the central nervous system in rats. Journal of Spinal Cord Medicine, 37(1), 93-100.
  - Li, B., Maafi, F., Berti, R., Pouliot, P., Rheaume, E., Tardif, J.-C., & Lesage, F. (2014). Hybrid FMT-MRI applied to in vivo atherosclerosis imaging. Biomedical Optics Express, 5(5), 1664-1676.
  - Sakadzic, S., Mandeville, E. T., Gagnon, L., Musacchia, J. J., Yaseen, M. A., Yucel, M. A., Lefebvre, J., Lesage, F., Dale, A. M., Eikermann-Haerter, K., Ayata, C., Srinivasan, V. J., Lo, E. H., Devor, A., & Boas, D. A. (2014). Large arteriolar component of oxygen delivery implies a safe margin of oxygen supply to cerebral tissue. Nature Communications, 5(1), 5734.
  - Kamrani, E., Lesage, F., & Sawan, M. (2014). Low-Noise, High-Gain Transimpedance Amplifier Integrated With SiAPD for Low-Intensity Near-Infrared Light Detection. IEEE Sensors Journal, 14(1), 258-269.
  - Ng, V. W. K., Avti, P. K., Bedard, M., Lam, T., Rouleau, L., Tardif, J.-C., Rheaume, E., Lesage, F., & Kakkar, A. (2014). Miktoarm star conjugated multifunctional gold nanoshells: Synthesis and an evaluation of biocompatibility and cellular uptake. Journal of Materials Chemistry B, 2(37), 6334-6344.
  - Li, B., Pouliot, P., & Lesage, F. (2014). MRI-guided fiber-based fluorescence molecular tomography for preclinical atherosclerosis imaging. Photonics North 2014, 9288, 92880r.
  - Desjardins, M., Berti, R., Pouliot, P., Dubeau, S., & Lesage, F. (2014). Multimodal study of the hemodynamic response to hypercapnia in anesthetized aged rats. Neuroscience Letters, 563, 33-37.
  - Castonguay, A., Thomas, S., Lesage, F., & Casanova, C. (2014). Repetitive and Retinotopically Restricted Activation of the Dorsal Lateral Geniculate Nucleus with Optogenetics. PLOS One, 9(4).
  - Lee, J., Jiang, J. Y., Wu, W., Lesage, F., & Boas, D. A. (2014). Statistical intensity variation analysis for rapid volumetric imaging of capillary network flux. Biomedical Optics Express, 5(4), 1160-1172.
  - Li, B., Berti, R., Abran, M., & Lesage, F. (2014). Ultrasound guided fluorescence molecular tomography with improved quantification by an attenuation compensated born-normalization and in vivo preclinical study of cancer. Review of Scientific Instruments, 85(5).
- 2013
  - Lague-Beauvais, M., Brunet, J., Gagnon, L., Lesage, F., & Bherer, L. (2013). A fNIRS investigation of switching and inhibition during the modified stroop task in younger and older adults. NeuroImage, 64, 485-495.
  - Sadekova, N., Vallerand, D., Guevara, E., Lesage, F., & Girouard, H. (2013). Carotid calcification in mice: a new model to study the effects of arterial stiffness on the brain. Journal of the American Heart Association, 2(3), e000224.
  - Kamrani, E., Lesage, F., & Sawan, M. (2013). Efficient premature edge breakdown prevention technique for SiAPD fabrication using standard CMOS process. IOP International Journal of Semiconductor Science and Technology, 28(4).
  - Ng, V. W. K., Berti, R., Lesage, F., & Kakkar, A. (2013). Gold: A versatile tool for in vivo imaging. Journal of Materials Chemistry B, 1(1), 9-25.
  - Guevara, E., Berti, R., Londono, I., Xie, N., Bellec, P., Lesage, F., & Lodygensky, G. A. (2013). Imaging of an inflammatory injury in the newborn rat brain with photoacoustic tomography. PLOS One, 8(12).
  - Lee, J., Wu, W., Lesage, F., & Boas, D. A. (2013). Multiple-capillary measurement of RBC speed, flux, and hematocrit with optical coherence tomography. Journal of Cerebral Blood Flow & Metabolism, 33(11), 1707-1710.
  - El Helou, J., Belanger-Nelson, E., Freyburger, M., Dorsaz, S., Curie, T., La Spada, F., Gaudreault, P. O., Beaumont, E., Pouliot, P., Lesage, F., Frank, M. G., Franken, P., & Mongrain, V. (2013). Neuroligin-1 Links Neuronal Activity to Sleep-Wake Regulation. Proceedings of the National Academy of Sciences of the United States of America, 110(24), 9974-9979.
  - Nguyen, D. K., Tremblay, J., Pouliot, P., Vannasing, P., Florea, O., Carmant, L., Lepore, F., Sawan, M., Lesage, F., & Lassonde, M. (2013). Noninvasive Continuous Functional Near-Infrared Spectroscopy Combined With Electroencephalography Recording of Frontal Lobe Seizures. Epilepsia, 54(2), 331-340.
  - Guevara, E., Pouliot, P., Nguyen, D. K., & Lesage, F. (2013). Optical imaging of acute epileptic networks in mice. Journal of Biomedical Optics, 18(7), 76021-1.
  - Guevara, E., Sadekova, N., Girouard, H., & Lesage, F. (2013). Optical imaging of resting-state functional connectivity in a novel arterial stiffness model. Biomedical Optics Express, 4(11), 2332-2346.
  - Lam, T., Pouliot, P., Avti, P. K., Lesage, F., & Kakkar, A. K. (2013). Superparamagnetic Iron Oxide Based Nanoprobes for Imaging and Theranostics. Advances in Colloid and Interface Science, 199, 95-113.
  - Rouleau, L., Berti, R., Ng, V. W. K., Matteau-Pelletier, C., Lam, T., Savoural, P., Kakkar, A., Lesage, F., Rhéaume, E., & Tardif, J.-C. (2013). VCAM-1-targeting gold nanoshell probe for photoacoustic imaging of atherosclerotic plaque in mice. Contrast Media and Molecular Imaging, 8(1), 27-39.
  - Sawan, M., Salam, M. T., Le Lan, J., Kassab, A., Gelinas, S., Lesage, F., & Nguyen, D. K. (2013). Wireless recording systems : from non-invasive EEG-NIRS to invasive EEG devices. IEEE Transactions on Biomedical Circuits and Systems, 7(2), 186-195.
- 2012
  - Bolduc, V., Baraghis, E., Duquette, N., Thorin-Trescases, N., Lambert, J., Lesage, F., & Thorin, E. (2012). Catechin Prevents Severe Dyslipidemia-Associated Changes in Wall Biomechanics of Cerebral Arteries in Ldlr-/-:Hapob(+/+) Mice and Improves Cerebral Blood Flow. American Journal of Physiology-Heart and Circulatory Physiology, 302(6), H1330-H1339.
  - Bonnery, C., Leclerc, P.-O., Desjardins, M., Hoge, R., Bherer, L., Pouliot, P., & Lesage, F. (2012). Changes in Diffusion Path Length With Old Age in Diffuse Optical Tomography. Journal of Biomedical Optics, 17(5), 056002 (8 pages).
  - Kahlaoui, K., Di Sante, G., Barbeau, J., Maheux, M., Lesage, F., Ska, B., & Joanette, Y. (2012). Contribution of Nirs to the Study of Prefrontal Cortex for Verbal Fluency in Aging. Brain and Language, 121(2), 164-173.
  - Kamrani, E., Lesage, F., & Sawan, M. (2012). Fully on-chip integrated photodetector front-end dedicated to real-time portable optical brain imaging. Optics and Photonics Journal, 2(4), 300-313.
  - Gagnon, C., Desjardins-Crepeau, L., Tournier, I., Desjardins, M., Lesage, F., Greenwood, C. E., & Bherer, L. (2012). Near-Infrared Imaging of the Effects of Glucose Ingestion and Regulation on Prefrontal Activation During Dual-Task Execution in Healthy Fasting Older Adults. Behavioural Brain Research, 232(1), 137-147.
  - Scherer, L. C., Fonseca, R. P., Giroux, F., Senhadji, N., Marcotte, K., Tomitch, L. M., Benali, H., Lesage, F., Ska, B., & Joanette, Y. (2012). Neurofunctional (re)organization underlying narrative discourse processing in aging: Evidence from fNIRS. Brain and Language, 121(2), 174-184.
  - Dubeau, S., Havlicek, M., Beaumont, E., Ferland, G., Lesage, F., & Pouliot, P. (2012). Neurovascular Deconvolution of Optical Signals as a Proxy for the True Neuronal Inputs. Journal of Neuroscience Methods, 210(2), 247-258.
  - Nguyen, D. K., Tremblay, J., Pouliot, P., Vannasing, P., Florea, O., Carmant, L., Lepore, F., Sawan, M., Lesage, F., & Lassonde, M. (2012). Non-Invasive Continuous EEG-fNIRS Recording of Temporal Lobe Seizures. Epilepsy Research, 99(1-2), 112-126.
  - Pouliot, P., Tremblay, J., Robert, M., Vannasing, P., Lepore, F., Lassonde, M., Sawan, M., Khoa Nguyen, D., & Lesage, F. (2012). Nonlinear hemodynamic responses in human epilepsy: a multimodal analysis With fNIRS-EEG and fMRI-EEG. Journal of Neuroscience Methods, 204(2), 326-340.
  - Desjardins, M., Pouliot, P., & Lesage, F. (2012). Principles and Applications of Diffuse Optical Imaging for the Brain. Current Medical Imaging Reviews, 8(3), 157-173.
  - Scherer, L. C., Fonseca, R. P., Amiri, M., Adrover-Roig, D., Marcotte, K., Giroux, F., Senhadji, N., Benali, H., Lesage, F., & Ansaldo, A. I. (2012). Syntactic processing in bilinguals: An fNIRS study. Brain and Language, 121(2), 144-151.
  - Payette, J., Peau, L. D. C., Mekary, S., Lesage, F., Hoge, R., Desjardins, M., Gauthier, C., & Bherer, L. (2012). The Positive Effect of Physical Fitness on Executive Functions in Healthy Younger and Older Women. Gerontologist, 52, 585-585.
- 2011
  - Dubeau, S., Desjardins, M., Pouliot, P., Beaumont, E., Gaudreau, P., Ferland, G., & Lesage, F. (2011). Biophysical model estimation of neurovascular parameters in a rat model of healthy aging. NeuroImage, 57(4), 1480-1491.
  - Drouin, A., Bolduc, V., Thorin-Trescases, N., Bélanger, E., Fernandes, P., Baraghis, E., Lesage, F., Gillis, M. A., Villeneuve, L., Hamel, E., Ferland, G., & Thorin, E. (2011). Catechin treatment improves cerebrovascular flow-mediated dilation and learning abilities in atherosclerotic mice. American Journal of Physiology : Heart and Circulatory Physiology, 300(3), H1032-H1043.
  - Dubeau, S., Ferland, G., Gaudreau, P., Beaumont, E., & Lesage, F. (2011). Cerebrovascular hemodynamic correlates of aging in the Lou/c rat: A model of healthy aging. NeuroImage, 56(4), 1892-1901.
  - Tardif, J. C., Lesage, F., Harel, F., Romeo, P., & Pressacco, J. (2011). Imaging biomarkers in atherosclerosis trials. Circulation: Cardiovascular Imaging, 4(3), 319-333.
  - Li, B., Abran, M., Matteau-Pelletier, C., Rouleau, L., Lam, T., Sharma, R., Rheaume, E., Kakkar, A., Tardif, J.-C., & Lesage, F. (2011). Low-cost three-dimensional imaging system combining fluorescence and ultrasound. Journal of Biomedical Optics, 16(12), 126010.
  - Baraghis, E., Bolduc, V., Lefebvre, J., Srinivasan, V. J., Boudoux, C., Thorin, E., & Lesage, F. (2011). Measurement of cerebral microvascular compliance in a model of atherosclerosis with optical coherence tomography. Biomedical Optics Express, 2(11), 3079-3093.
  - Lareau, E., Lesage, F., Pouliot, P., Nguyen, D., Le Lan, J., & Sawan, M. (2011). Multichannel wearable system dedicated for simultaneous electroencephalographynear-infrared spectroscopy real-time data acquisitions. Journal of Biomedical Optics, 16(9), 096014.
  - Dehaes, M., Gagnon, L., Lesage, F., Pélégrini-Issac, M., Vignaud, A., Valabrègue, R., Grebe, R., Wallois, F., & Benali, H. (2011). Quantitative investigation of the effect of the extra-cerebral vasculature in diffuse optical imaging : a simulation study. Biomedical Optics Express, 2(3), 680-695.
  - Baraghis, E., Devor, A., Fang, Q., Srinivasan, V. J., Wu, W., Lesage, F., Ayata, C., Kasischke, K. A., Boas, D. A., & Sakadzic, S. (2011). Two-photon microscopy of cortical NADH fluorescence intensity changes: Correcting contamination from the hemodynamic response. Journal of Biomedical Optics, 16(10), 106003.
- 2010
  - Goguin, A., Lesage, F., Leblond, H., Pelegrini-Issac, M., Rossignol, S., & Benali, H. (2010). A Low-cost Implantable Near-infrared Imaging System of Spinal Cord Activity in the Cat. IEEE Transactions on Biomedical Circuits and Systems, 4(5), 329-335.
  - Vanni, M. P., Provost, J., Casanova, C., & Lesage, F. (2010). Bimodal modulation and continuous stimulation in optical imaging to map direction selectivity. NeuroImage, 49(2), 1416-1431.
  - Brieu, N., Beaumont, E., Dubeau, S., Cohen-Adad, J., & Lesage, F. (2010). Characterization of the hemodynamic response in the rat lumbar spinal cord using intrinsic optical imaging and laser speckle. Journal of Neuroscience Methods, 191(2), 151-157.
  - Vanni, M. P., Provost, J., Lesage, F., & Casanova, C. (2010). Evaluation of Receptive Field Size From Higher Harmonics in Visuotopic Mapping Using Continuous Stimulation Optical Imaging. Journal of Neuroscience Methods, 189(1), 138-150.
  - Venugopal, V., Chen, J., Lesage, F., & Intes, X. (2010). Full-field time-resolved fluorescence tomography of small animals. Optics Letters, 35(19), 3189-3191.
  - Ouakli, N., Guevara, E., Dubeau, S., Beaumont, E., & Lesage, F. (2010). Laminar optical tomography of the hemodynamic response in the lumbar spinal cord of rats. Optics Express, 18(10), 10068-10077.
  - Belanger, S., Abran, M., Intes, X., Casanova, C., & Lesage, F. (2010). Real-time diffuse optical tomography based on structured illumination. Journal of Biomedical Optics, 15(1), 016006.
  - Chen, J., Venugopal, V., Lesage, F., & Intes, X. (2010). Time-resolved diffuse optical tomography with patternedlight illumination and detection. Optics Letters, 35(13), 2121-2123.
  - Lina, J. M., Matteau-Pelletier, C., Dehaes, M., Desjardins, M., & Lesage, F. (2010). Wavelet-based estimation of the hemodynamic responses in diffuse optical imaging. Medical Image Analysis, 14(4), 606-616.
- 2009
  - Matteau-Pelletier, C., Dehaes, M., Lesage, F., & Lina, J.-M. (2009). 1/f noise in diffuse optical imaging and wavelet-based response estimation. IEEE Transactions on Medical Imaging, 28(3), 415-422.
  - Lesage, F., Brieu, N., Dubeau, S., & Beaumont, E. (2009). Optical Imaging of Vascular and Metabolic Responses in the Lumbar Spinal Cord After T10 Transection in Rats. Neuroscience Letters, 454(1), 105-109.
  - Provost, J., & Lesage, F. (2009). The application of compressed sensing for photo-acoustic tomography. IEEE Transactions on Medical Imaging, 28(4), 585-594.
- 2008
  - Lina, J. M., Dehaes, M., Matteau-Pelletier, C., & Lesage, F. (2008). Complex Wavelets Applied to Diffuse Optical Spectroscopy for Brain Activity Detection. Optics Express, 16(2), 1029-1050.
  - Gagnon, L., Gauthier, C., Hoge, R. D., Lesage, F., Selb, J., & Boas, D. A. (2008). Double-layer estimation of intra- and extracerebral hemoglobin concentration with a time-resolved system. Journal of Biomedical Optics, 13(5), 054019.
  - Kahlaoui, K., Vlasblom, V., Lesage, F., Senhadji, N., Benali, H., & Joanette, Y. (2008). Hemispheric specialization for the semantic processing of words during aging: A near-infrared spectroscopy study. Brain and Cognition, 67.
  - Gagnon, L., Desjardins, M., Jehanne-Lacasse, J., Bherer, L., & Lesage, F. (2008). Investigation of Diffuse Correlation Spectroscopy in Multi-Layered Media Including the Human Head. Optics Express, 16(20), 15514-15530.
  - Gallagher, A., Lassonde, M., Bastien, D., Vannasing, P., Lesage, F., Grova, C., Bouthillier, A., Carmant, L., Lepore, F., Beland, R., & Nguyen, D. K. (2008). Non-Invasive Pre-Surgical Investigation of a 10 Year-Old Epileptic Boy Using Simultaneous Eeg-Nirs. Seizure-European Journal of Epilepsy, 17(6), 576-582.
- 2007
  - Cohen-Adad, J., Chapuisat, S., Doyon, J., Rossignol, S., Lina, J. M., Benali, H., & Lesage, F. (2007). Activation detection in diffuse optical imaging by means of the general linear model. Medical Image Analysis, 11(6), 616-629.
  - Scherer, L. C., Ska, B., Giroux, F., Lesage, F., Senhadji, N., Marcotte, K., Tomitch, L. M. B., Benali, H., & Joanette, Y. (2007). Discourse Comprehension in Successful Aging: a NIRS Study. Brain and Language, 103(1-2), 228-229.
  - Akers, W., Lesage, F., Holten, D., & Achilefu, S. (2007). In Vivo Resolution of Multiexponential Decays of Multiple Near-Infrared Molecular Probes by Fluorescence Lifetime-Gated Whole-Body Time-Resolved Diffuse Optical Imaging. Molecular Imaging, 6(4), 237-246.
  - Kahlaoui, K., Vlasblom, V., Lesage, F., Senhadji, N., Benali, H., & Joanette, Y. (2007). Semantic Processing of Words in Spectroscopy the Aging Brain: a Near-Infrared (NIRS) Study. Brain and Language, 103(1-2), 144-145.
- 2006
  - Scherer, L. C., Giroux, F., Lesage, F., Senhadji, N., Benali, H., & Ansaldo, A. I. (2006). An optical imaging study of semantic and syntactic processing by bilinguals. Brain and Language, 99(1-2), 197-198.
  - Kahlaoui, K., Lesage, F., Senhadji, N., Benall, H., & Joanette, Y. (2006). Hemispheric specialization for the semantic processing of words: A near-infrared spectroscopy (NIRS) study. Brain and Language, 99(1-2), 193-194.
Conference papers (109)
- 2023
  - Lemoine, E., Toffa, D. H., Lesage, F., Nguyen, D. K., & Assi, E. B. (2023, April). Predicting Seizure Freedom through Computational Processing of Routine EEG [Abstract]. 2023 Annual Meeting Abstracts (3 pages). Published in Neurology, 100(17, suppl ).
- 2022
  - Bourourou, M., Khouider, M., Lesage, F., & Hamel, E. (2022, May). Cerebrovascular disease affects resting-state functional connectivity and neurovascular coupling, but not neuronal activity and memory [Poster]. BRAIN & BRAIN PET 2022, Glasgow, Scotland. Published in Journal of Cerebral Blood Flow and Metabolism, 42(1S).
  - Zimmer, A., Bourourou, M., Lesage, F., & Hamel, E. (2022, May). Neurovascular coupling and functional connectivity changes during Alzheimer disease progression: Effects of simvastatin treatment [Poster]. BRAIN & BRAIN PET 2022, Glasgow, Scotland (1 page). Published in Journal of Cerebral Blood Flow and Metabolism, 42(1S).
- 2021
  - Soucy, J.‐.P., Chevrefils, C., Osseiran, S., Sylvestre, J.‐.P., Lesage, F., Beaulieu, S., Pascoal, T. A., Provost, K., Arbour, J. D., Rhéaume, M.‐.A., Villeneuve, S., Nasreddine, Z. S., Rosa‐Neto, P., Gauthier, S., Robillard, A., Chayer, C., Black, S. E., Kertes, P. J., El Shahawy, H., ... Ritter, A. (2021, July). A retinal deep phenotyping TM platform to predict the cerebral amyloid PET status in older adults [Poster]. Alzheimer's Association International Conference (AAIC 2021), Denver, Colorado (2 pages). Published in Alzheimer's & Dementia, 17(S5).
  - Marchand, P.-J., Lu, X., Zhang, C., & Lesage, F. (2021, March). Characterization of RBC flux and velocity measurements in OCT with concurrent two-photon microscopy [Paper]. Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXV (8 pages).
  - Gagliano, L., Lesage, F., Nguyen, D. K., Sawan, M., & Assi, E. B. (2021, August). Combining bispectral magnitude and entropy measures to improve classification of preictal and ictal iEEG [Paper]. 34th International Epilepsy Congress (1 page). Published in Epilepsia, 62(S3).
  - Lemoine, E., Tessier, J.-D., Pelletier-Mc Duff, G., Robert, M., Toffa, D., Lesage, F., Nguyen, D. K., & Assi, E. B. Entropy on routine EEG: a fingerprint of recent seizure activity? [Abstract]. 34th International Epilepsy Congress (1 page). Published in Epilepsia, 62(S3).
  - Shokooh, L. A., Toffa, D., Lesage, F., & Nguyen, D. K. Identifying different seizure onset and termination patterns and detecting the driver region preceding different onset patterns [Abstract]. 34th International Epilepsy Congress (1 page). Published in Epilepsia, 62(S3).
  - Lefebvre, J., Delafontaine-Martel, P., Lemieux, P., Descoteaux, M., Petit, L., & Lesage, F. (2021, March). Localization and imaging of white matter fiber crossings in whole mouse brains using diffusion MRI and serial blockface OCT [Paper]. Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics 2021 (8 pages).
  - Delafontaine-Martel, P., Lu, X., Zhang, C., Damseh, R., Lesage, F., & Marchand, P. (2021, March). Multiphoton excitation of Rose Bengal to induce capillary photo-thrombosis [Paper]. Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics (6 pages).
- 2020
  - Damseh, R., Delafontaine-Martel, P., James-Marchand, P., Sirpal, P., Cheriet, F., & Lesage, F. (2020, July). Automated Analysis of Brain Microvasculature: From Segmentation to Anatomical Modeling [Paper]. 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society (EMBC 2020), Montréal, Qc, Canada.
  - Laurence, A., Peng, K., Toffa, D., Robert, M., Lesage, F., Bouthillier, A., Nguyen, D. K., & Leblond, F. (2020, April). Localization of epileptic activity based on hemodynamics using an intraoperative hyperspectral imaging system [Paper]. Clinical and Translational Biophotonics, Washington, D.C..
  - Damseh, R., Cheriet, F., & Lesage, F. (2020, April). Modeling the Topology of Cerebral Microvessels Via Geometric Graph Contraction [Paper]. 17th IEEE International Symposium on Biomedical Imaging (ISBI 2020), Iowa City, IA.
  - Gagliano, L., Lesage, F., Assi, E. B., Nguyen, D. K., & Sawan, M. (2020, June). Neural networks for epileptic seizure prediction: algorithms and hardware implementation [Paper]. 18th IEEE International New Circuits and Systems Conference (NEWCAS 2020), Montréal, Qc, Canada.
- 2019
  - Belgharbi, H., Porée, J., Damseh, R., Delafontaine-Martel, P., Lesage, F., & Provost, J. (2019, January). Anatomically realistic simulation framework for ultrasound localization microscopy [Abstract]. Acoustical Society of America Meeting. Published in Journal of the Acoustical Society of America, 146(4).
  - Lu, X., Moeini, M., Li, B., de Montgolfier, O., Lu, Y., Thorin, E., & Lesage, F. (2019, July). Brain tissue oxygenation is modulated by voluntary exercise in AD awake mice [Abstract]. 29th International Symposium on Cerebral Blood Flow, Metabolism and Function / 14th International Conference on Quantification of Brain Function with PET (BRAIN 2019 and BRAIN Pet 2019), Yokohama, JAPAN. Published in Journal of Cerebral Blood Flow and Metabolism, 39(1_suppl).
  - Sharafi, S. M., Sylvestre, J. P., Chevrefils, C., Soucy, J. P., & Lesage, F. (2019, January). Correlation between PET-derived cerebral amyloid status and retinal image features using a hyperspectral fundus camera [Paper]. Clinical and Translational Neurophotonics, San Francisco, California.
  - Bourourou, M., Khouider, M., Machado, A., Lesage, F., Lecrux, C., & Hamel, E. (2019, July). Deciphering the role of neurons and vessels in neurovascular coupling in cerebrovascular disease through aging [Abstract]. 29th International Symposium on Cerebral Blood Flow, Metabolism and Function / 14th International Conference on Quantification of Brain Function with PET (BRAIN 2019 and BRAIN Pet 2019), Yokohama, JAPAN. Published in Journal of Cerebral Blood Flow and Metabolism, 39(1_suppl).
  - Lu, X., Moeini, M., Li, B., Lu, Y., Damseh, R., Pouliot, P., Thorin, E., & Lesage, F. (2019, July). Effect of exercise on capillary red blood cell dynamics in transgenic ad mice [Abstract]. 29th International Symposium on Cerebral Blood Flow, Metabolism and Function / 14th International Conference on Quantification of Brain Function with PET (BRAIN 2019 and BRAIN Pet 2019), Yokohama, JAPAN. Published in Journal of Cerebral Blood Flow and Metabolism, 39(1_suppl).
  - Saha, S., Sawan, M., & Lesage, F. (2019, April). Integrated CMOS TD-NIRS using 1.5D interposer technology [Paper]. Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA, BRAIN, NTM, OMA, OMP), Tucson, Arizona.
  - Lecrux, C., Bourourou, M., Lesage, F., & Hamel, E. (2019, July). Noradrenergic deficit affects whisker-evoked neurovascular coupling responses [Abstract]. 29th International Symposium on Cerebral Blood Flow, Metabolism and Function / 14th International Conference on Quantification of Brain Function with PET (BRAIN 2019 and BRAIN Pet 2019), Yokohama, JAPAN. Published in Journal of Cerebral Blood Flow and Metabolism, 39(1_suppl).
  - Saha, S., Burri, S., Bruschini, C., Charbon, E., Lesage, F., & Sawan, M. (2019, April). Time Domain NIRS Optode based on Null/Small Source-Detector Distance for Wearable Applications [Paper]. 40th Annual IEEE Custom Integrated Circuits Conference (CICC 2019), Austin, TX, United states (8 pages).
- 2018
  - Lu, Y., Abran, M., Cloutier, G., & Lesage, F. (2018, January). Catheter-based time-gated near-infrared fluorescence/OCT imaging system [Paper]. Diagnostic and Therapeutic Applications of Light in Cardiology, San Francisco, CA.
  - Lu, X., Moeini, M., Li, B., Zhang, C., Sakadic, S., & Lesage, F. (2018, January). 3D brain oxygenation measurements in awake hypertensive mice using two photon phosphorescence lifetime imaging [Paper]. Multiphoton Microscopy in the Biomedical Sciences XVIII, San Francisco, CA, United states (6 pages).
  - Damseh, R., Cheriet, F., & Lesage, F. (2018, July). Fully Convolutional DenseNets for Segmentation of Microvessels in Two-photon Microscopy [Paper]. 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2018), Honolulu, HI.
  - Lefebvre, J., Castonguay, A., & Lesage, F. (2018, February). Imaging whole mouse brains with a dual resolution serial swept-source optical coherence tomography scanner [Paper]. SPIE BiOS, San Francisco, California, USA (9 pages).
  - Zhang, C., Tabatabaei, M., Belanger, S., Girouard, H., Moeini, M., Lu, X., & Lesage, F. (2018, January). In vivo measurement of astrocytic endfoot Ca2+and parenchymal vessel responses during 4-AP induced epilepsy using two-photon fluorescence lifetime microscopy [Paper]. Multiphoton Microscopy in the Biomedical Sciences XVIII, San Francisco, CA, United states (7 pages).
  - Delafontaine-Martel, P., Lefebvre, J., Damseh, R., Castonguay, A., Tardif, P.-L., & Lesage, F. (2018, January). Large scale serial two-photon microscopy to investigate local vascular changes in whole rodent brain models of Alzheimer's disease [Paper]. Multiphoton Microscopy in the Biomedical Sciences XVIII, San Francisco, CA, United states.
  - Saha, S., Lesage, F., & Sawan, M. (2018, October). Live Demonstration: Miniaturized Compact NIRS probe based on SiPM and Pulsed VCSEL diode routes to wearable devices [Paper]. IEEE Biomedical Circuits and Systems Conference (BioCAS 2018), Cleveland, OH.
  - Saha, S., Yuankang, L., Weyers, S., Lesage, F., & Sawan, M. (2018, October). Miniaturized probe for time-domain near-infrared spectroscopy [Paper]. IEEE Biomedical Circuits and Systems Conference (BioCAS 2018), Cleveland, OH (4 pages).
  - Lu, X., Moeini, M., Li, B., Sakadžić, S., & Lesage, F. (2018, February). Voluntary exercise confers protection against age-related deficits in brain oxygenation in awake mice model of Alzheimer's disease [Paper]. 2018 SPIE BiOS, San Francisco, California, USA (6 pages).
- 2017
  - Lefebvre, J., Delafontaine-Martel, P., Castonguay, A., & Lesage, F. (2017, November). Automated serial blockface histology : acquisition, reconstruction and application [Poster]. Big Brain Workshop, Montréal, Québec.
  - Moeini, M., Lu, X., Lam, T., Belanger, S., Kakkar, A., & Lesage, F. (2017, April). Brain tissue oxygenation changes with age in awake mice [Paper]. 28th Symposium on Cerebral Blood Flow, Metabolism and Function & 13th Conference on Quantification of Brain Function with PET (BRAIN & BRAIN PET 2017), Berlin, Germany. Published in Journal of Cerebral Blood Flow and Metabolism, 37(S1).
  - Flores-Castro, A., Peng, K., Nguyen, D. K., Lesage, F., Pouliot, P., Rosas-Romero, R., & Guevara, E. (2017, February). Detecting epileptic seizures in advance using optical and electrical recordings [Paper]. 27th International Conference on Electronics, Communications and Computers (CONIELECOMP 2017), Puebla, Mexico (4 pages).
  - Farah, R., Belanger, S., Jafari, R., Chevrefils, C., Sylvestre, J. P., Lesage, F., & Cheriet, F. (2017, July). Retinal vessel segmentation from a hyperspectral camera images [Paper]. Image Analysis and Recognition. 14th International Conference (ICIAR 2017), Montréal, Québec.
  - Luo, Q., Ding, J., Lu, X., Li, B., Moeini, M., & Lesage, F. (2017, January). Simultaneous two-photon imaging of cerebral oxygenation and capillary blood flow in atherosclerotic mice [Paper]. Neural Imaging and Sensing, San Francisco, California.
  - Pinto, M., Aubertin, K., Desroches, J., Jermyn, M., Trinh, V. Q., Vladoiu, M. C., Grosset, A. A., Lavallee, A. P., Benzyane, I., Benzyane, I., Benzyane, I., Faci, N., Richard, M. E., Duong, L., Haas, C., Badawy, Y., Saad, F., Zorn, K., Lesage, F., ... Trudel, D. (2017, April). Towards live detection of cancerous tissue during radical prostatectomy using a raman spectroscopy probe [Paper]. Bio-Optics: Design and Application (BODA 2017), San Diego, CA, United states.
  - Lefebvre, J., Castonguay, A., & Lesage, F. (2017, January). White matter segmentation by estimating tissue optical attenuation from volumetric OCT massive histology of whole rodent brains [Paper]. Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXIV, USA (9 pages).
- 2016
  - Moeini, M., Tabatabaei, M., Kakkar, A., & Lesage, F. (2016, April). Capillary substrate of brain tissue oxygenation changes with age [Paper]. Biomedical Optics 2016, Fort Lauderdale, Florida.
  - Auger, H., Bherer, L., Boucher, E., Hoge, R., Lesage, F., & Dehaes, M. (2016, April). Contribution of extra-cerebral and cerebral hemodynamic signals during exercise quantified with time-domain near infrared spectroscopy [Paper]. Optics and the Brain, part of Biomedical Optics 2016, Fort Lauderdale, Florida United States.
  - Saha, S., Lesage, F., & Sawan, M. (2016, February). High-voltage pulse generator with variable delay for ultrafast gating of single photon detector [Paper]. 7th IEEE Latin American Symposium on Circuits & Systems (LASCAS 2016), Florianopolis, Brazil.
  - Gagnon, L., Sakadzic, S., Lesage, F., Pouliot, P., Dale, A. M., Devor, A., Buxton, R., & Boas, D. A. (2016, April). Improving the calibrated fMRI estimation of CMRO₂ with oxygen-sensitive two-photon microscopy [Paper]. Cancer Imaging and Therapy, part of Biomedical Optics 2016, Fort Lauderdale, Florida, United States.
  - Laurence, A., Pichette, J., Angulo-Rodríguez, L. M., Saint Pierre, C., Lesage, F., Bouthillier, A., Nguyen, D. K., & Leblond, F. (2016, February). Intraoperative brain hemodynamic response assessment with real-time hyperspectral optical imaging [Paper]. Clinical and Translational Neurophotonics, part of Photonics West 2016, San Francisco, California, United States.
  - Saha, S., Lesage, F., & Sawan, M. (2016, May). Time-resolved reflectance using short source-detector separation [Paper]. IEEE International Symposium on Circuits and Systems (ISCAS 2016), Montréal, Québec.
- 2015
  - Moeini, M., Tabatabaei, M. S., Belanger, S., Avti, P., Castonguay, A., Pouliot, P., & Lesage, F. (2015, February). Effects of anesthesia on the cerebral capillary blood flow in young and old mice [Paper]. SPIE Conference on Multiphoton Microscopy in the Biomedical Sciences XV, San Francisco, California (6 pages).
  - Lesage, F. (2015, June). Investigating capillary dynamics with aging [Abstract]. 27th International Symposium on Cerebral Blood Flow, Metabolism and Function & 12th International Conference on Quantification of Brain Function with PET (BRAIN 2015), Vancouver, B.-C.. Published in Journal of Cerebral Blood Flow & Metabolism, 36(1_suppl).
  - Castonguay, A., Avti, P. K., Moeini, M., Pouliot, P., Tabatabaei, M. S., Belanger, S., & Lesage, F. (2015, February). Investigating the correlation between white matter and microvasculature changes in aging using large scale optical coherence tomography and confocal fluorescence imaging combined with tissue sectioning [Paper]. SPIE Conference on Imaging, Manipulation and Analysis of Biomolecules, Cells and Tissues XIII, San Francisco, California (6 pages).
  - Lesage, F., Castonguay, A., Tardif, P. L., Lefebvre, J., & Li, B. (2015, August). Investigating the impact of blood pressure increase to the brain using high resolution serial histology and image processing [Paper]. Wavelets and Sparsity XVI, San Diego, CA, United states.
  - Guevara, E., Sirpal, P., Abran, M., Pouliot, P., Lesage, F., Jin, C., Londono, I., & Lodygensky, G. A. (2015, June). White matter injury in a newborn rat model analyzed with Resting-State Optical Imaging of Intrinsic Signals (rsOIS) [Paper]. Photonics North 2015, Ottawa, ON, Canada.
- 2014
  - Sabouni, A., Pouliot, P., Shmuel, A., & Lesage, F. (2014, August). BRAIN initiative: Fast and parallel solver for real-time monitoring of the eddy current in the brain for TMS applications [Paper]. 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2014), Chicago, Illinois.
  - Beaulieu-Ouellet, E., Bélanger, S., Deterre, R., Gariépy, C., De Montigny, É., Leblond, F., Boudoux, C., & Lesage, F. (2014, February). Conference 8928A: Optical Techniques in Neurosurgery, Brain Imaging, and Neurobiology [Paper]. 2014 Photonics West, San Francisco, California.
  - Guevara, E., Manuel Gutierrez-Hernandez, J., Castonguay, A., Lesage, F., & Javier Gonzalez, F. (2014, May). Ex-vivo multi-modal microscopy of healthy skin [Paper]. Photonics North 2014, Montréal, Québec.
  - Sakadzic, S., Mandeville, E. T., Gagnon, L., Musacchia, J. J., Yaseen, M. A., Yucel, M. A., Lefebvre, J., Lesage, F., Dale, A. M., Eikermann-Haerter, K., Ayata, C., Srinivasan, V. J., Lo, E. H., Devor, A., & Boas, D. A. (2014, June). High-resolution optical microscopy imaging of cortical oxygen delivery and consumption [Paper]. 2014 Conference on Lasers and Electro-Optics, CLEO 2014 - Laser Science to Photonic Applications, San Jose, California, USA (3 pages).
  - Desjardins, M., Berti, R., Lefebvre, J., Dubeau, S., & Lesage, F. (2014, April). Microscopic Dynamics of Cerebral Capillary Blood Flow in Aged Anesthetized Rats [Paper]. Biomedical Optics 2014, Miami, Florida United States.
  - Guevara, E., Berti, R., Londono, I., Ningshi, X., Bellec, P., Lesage, F., & Lodygensky, G. A. (2014, May). Photoacoustic imaging of an inflammatory lesion model in the neonatal rat brain [Paper]. Photonics North 2014, Montréal, Québec.
  - Thorin, E., Bolduc, V., Cole, W., Lesage, F., & Raignault, A. (2014, September). Pulse pressure increases shear stress sensitivity of isolated mouse cerebral arteries [Abstract]. 11th International Symposium on Resistance Arteries: From Molecular Machinery to Clinical Challenges, Banff, Alberta. Published in Journal of Vascular Research, 51(S2).
- 2013
  - Sabouni, A., Venkateswaran, A., Shmuel, A., Pouliot, P., & Lesage, F. (2013, July). An automated technique to determine the induced current in transcranial magnetic stimulation [Paper]. IEEE Antennas and Propagation Society International Symposium (APSURSI 2013), Orlando, FL, USA (2 pages).
  - Kamrani, E., Chaddad, A., Lesage, F., & Sawan, M. (2013, May). Integrated transimpedance amplifiers dedicated to low-noise and low-power biomedical applications [Paper]. 29th Southern Biomedical Engineering Conference (SBEC 2013), Miami, FL, USA.
  - Kamrani, E., Hamady, M., Lesage, F., & Sawan, M. (2013, May). Modeling and characterizing optical CMOS, sensors for biomedical low-intensity light detection [Paper]. 29th Southern Biomedical Engineering Conference (SBEC 2013), Miami, FL, USA.
  - Kamrani, E., Lesage, F., & Sawan, M. (2013, May). On-chip single photon counting electronic circuitry dedicated to real-time brain imaging applications [Paper]. 29th Southern Biomedical Engineering Conference (SBEC 2013), Miami, FL, USA.
  - Kamrani, E., Lesage, F., & Sawan, M. (2013, July). Towards on-chip integration of brain imaging photodetectors using standard CMOS process [Paper]. 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2013), Osaka, Japon.
- 2012
  - Amiri, M., Bonnéry, C., Pouliot, P., Wilson, M., Lesage, F., & Joanette, Y. (2012, October). An event-related fNIRS approach to the study of word processing in aging: preliminary results looking at concreteness [Paper]. 50th Annual Meeting of the Academy of Aphasia, San Francisco, CA, USA.
  - Pouliot, P., Truong Van, T., Zhang, C., Dubeau, S., Nguyen, D. K., & Lesage, F. (2012, April). Biophysical Model Estimation from Multispectral Intrinsic Optical Imaging in a Rat Model of Epilepsy [Paper]. Biomedical Optics Conference paper, Miami, FL, USA.
  - Sawan, M., Salam, M. T., Gelinas, S., Le Lan, J., Lesage, F., & Nguken, D. K. (2012, May). Combined NIRS-EEG remote recordings for epilepsy and stroke real-time monitoring [Paper]. IEEE International Symposium on Circuits and Systems (ISCAS 2012), Seoul, Korea.
  - Lesage, F., Bonnery, C., & Pouliot, P. (2012, January). Diffuse optical tomography and biophysical modeling of the aging brain [Paper]. 4th International Conference onf the Development of Biomedical Engineering, Ho Chi Minh City, Vietnam.
  - Kamrani, E., Yun, S. H. A., Lesage, F., & Sawan, M. (2012, September). Fast photodetection in functional near infra-red spectroscopy [Paper]. 11th International Conference on Infrared Optoelectronics: Materials and Devices (MIOMD 2012), Evanston, Il. USA.
  - Spinelli, L., Botwicz, M., Zolek, N., Kacprzak, M., Milej, D., Liebert, A., Weigel, U., Durduran, T., Foschum, F., Kienle, A., Baribeau, F., Leclair, S., Bouchard, J.-P., Noiseux, I., Gallant, P., Mermut, O., Pifferi, A., Torricelli, A., Cubeddu, R., ... Zaccanti, G. (2012, April). Inter-laboratory comparison of optical properties performed on intralipid and India Ink [Paper]. Biomedical Optics Conference paper, Miami, FL, USA.
  - Lesage, F., Dubeau, S., Zhang, C., Baraghis, E., Ferland, G., Gaudreau, P., & Pouliot, P. (2012, April). Intrinsic optical imaging and Doppler OCT assessment of vascular reactivity with aging under caloric restriction [Paper]. Biomedical Optics Conference paper, Miami, FL, USA.
  - Kamrani, E., Yun, S. H. A., Lesage, F., & Sawan, M. (2012, September). Near infra-red light detection using silicon avalanche photodiodes: design challenges in standard CMOS technology [Paper]. 11th International Conference on Infrared Optoelectronics: Materials and Devices (MIOMD 2012), Chicago, IL. USA.
  - Kamrani, E., Yun, S. H. A., Lesage, F., & Sawan, M. (2012, September). Optimal-adaptive control system for low-noise, low-power and fast photodetection in functional near infra-red spectroscopy [Paper]. 11th International Conference on Infrared Optoelectronics: Materials and Devices (MIOMD 2012), Chicago, IL. USA.
  - Kamrani, E., Lesage, F., & Sawan, M. (2012, June). Premature edge breakdown prevention techniques in CMOS APD fabrication [Paper]. 10th IEEE International New Circuits and Systems Conference (NEWCAS 2012), Montréal, Québec.
  - Kamrani, E., Yun, S. H. A., Lesage, F., & Sawan, M. (2012, September). State-of-the-Art logarithmic transimpedance amplifier with automatic gain control and ambient light rejection for fNIRS [Paper]. 11th International Conference on Infrared Optoelectronics: Materials and Devices (MIOMD 2012), Evanston, Il. USA.
  - Pouliot, P., Truong Van, T., Zhang, C., Dubeau, S., & Lesage, F. (2012, June). Tight neurovascular coupling in a rat model of quasi-periodic interictal spiking using multispectral optical imaging [Paper]. Photonics North 2012, Montréal, Québec.
  - Ameri, M., Kamrani, E., Lesage, F., & Sawan, M. (2012, August). Ultra-fast quench-reset integrated circuit for high-speed single photon detection [Paper]. 55th IEEE International Midwest Symposium on Circuits and Systems (MWSCAS 2012), Boise, ID, USA.
  - Li, B., & Lesage, F. (2012, June). Ultrasound guided fluorescence tomography: system and reconstruction [Paper]. Photonics North 2012, Montréal, Québec.
- 2011
  - Hamelin, B., Archambault, S., Belanger, S., Lina, J. M., & Lesage, F. (2011, March). Application of compressed sensing to optical tomography [Paper]. 8th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI'11, Chicago, IL, United states.
  - Abran, M., Matteau-Pelletier, C., Zerouali-Boukhal, K., Tardif, J.-C., & Lesage, F. (2011, January). Combined acoustic-photoacoustic and fluorescence imaging catheter for the detection of the atherosclerotic plaque [Paper]. Photons Plus Ultrasound: Imaging and Sensing 2011, San Francisco, CA, United states.
  - Lareau, E., Simard, G., Lesage, F., Nguyen, D., & Sawan, M. (2011, March). Near infrared spectrometer combined with multichannel EEG for functional brain imaging [Paper]. 5th International Symposium on Medical Information and Communication Technology (ISMICT 2011), Montreux, Switzerland.
  - Dubeau, G., Ferland, P., Gaudreau, P., Beaumont, É., & Lesage, F. (2011, March). Quantification of cerebrovascular changes in the aging Lou/C rat using intrinsic optical imaging [Paper]. 10th International Conference on Alzheimers & Parkinson's Disease, Barcelona.
  - Baraghis, E., Bolduc, V., Gillis, M.-A., Srinivasan, V. J., Thorin, E., Boudoux, C., & Lesage, F. (2011, January). Synthetic reconstruction of dynamic blood flow in cortical arteries using optical coherence tomography for the evaluation of vessel compliance [Paper]. Photonic Therapeutics and Diagnostics VII, San Francisco, CA, United states.
  - Baraghis, E., Gillis, M. A., Sriinivasan, V., Thorin, E., Boudoux, C., & Lesage, F. (2011, January). Using optical coherence tomography to visualize dynamic blood flow and arterial compliance in cortical micro-vasculature in-vivo [Paper]. SPIE Photonics West 2011, San Francisco, California.
- 2010
  - Guevara, E., Abran, M., Belanger, S., Ouakli, N., & Lesage, F. (2010, January). Comparison of the performance of two depth-resolved optical imaging systems: laminar optical tomography and spatially modulated imaging [Paper]. Biomedical Applications of Light Scattering IV :, San Francisco, California, United States.
  - Rouleau, L., Saboural, P., Matteau-Pelletier, C., Baoqiang, L., Zerouali, K., Wang, T., Ng, V., Kakkar, A., Rhéaume, E., Tardif, J.-C., & Lesage, F. (2010, December). Nanoparticles applied to molecular imaging of the pathobiology of atherosclerosis [Paper]. 8th International Symposium on Bioscience and Nanotechnology, Japan.
- 2009
  - Lagüe-Beauvais, M., Brunnet, J., Gagnon, L., Dehaes, M., Lesage, F., & Bherer, L. (2009, July). Age-related differences and similarities in brain activation during inhibition and switching : A near infra-red spectroscopy study [Paper]. XIXth IAGG World Congress of Gerontology and Geriatrics, Paris.
  - Vanni, M., Provost, J., Belanger, S., Lesage, F., & Casanova, C. (2009, September). A new avenue in signal acquisition: coninuous stimulation combined with Fourier decomposition. Examples of optical imaging applications on the visual cortex [Paper]. World Molecular Imaging Conference, Montréal, Québec.
  - Desjardins, M., Gagnon, L., Gauthier, C., Hoge, R. D., Dehaes, M., Desjardins-Crepeau, L., Bherer, L., & Lesage, F. (2009, January). Application of a multicompartment dynamical model to multimodal optical imaging for investigating individual cerebrovascular properties [Paper]. Multimodal Biomedical Imaging IV.
  - Machado, A., Lesage, F., Lina, J., & Grova, C. (2009, December). Detection of hemodynamic responses to epileptic activity using EEG/NIRS simultaneous acquisitions [Paper]. Annual Meeting Amerian Association of Epilepsy.
  - Gagnon, L., Desjardins, M., Bherer, L., & Lesage, F. (2009, January). Double layer estimation of flow changes using diffuse correlation spectroscopy [Paper]. Optical Tomography and Spectroscopy of Tissue VIII.
  - Belanger, S., Abran, M., Intes, X., Casanova, C., & Lesage, F. (2009, September). Fast digital micromirror based diffuse optical tomography [Paper]. World Molecular Imaging Conference, Montréal, Québec.
  - Belanger, S., Abran, M., Intes, X., Casanova, C., & Lesage, F. (2009, October). Fast digital micromirror based laminar optical tomography [Paper]. Neurosciences 2009, Chicago.
  - Lagüe-Beauvais, M., Brunnet, J., Gagnon, L., Dehaes, M., Lesage, F., & Bherer, L. (2009, March). Inhibition and switching in younger and older adults : a near infra-red spectroscopy study [Paper]. 19th annual Rotman Research Institute Conference - Cognitive Spectroscopy Study, Toronto, Ontario.
  - Dubeau, S., Beaumont, E., & Lesage, F. (2009, January). Relation between the neuronal and hemodynamic response in the lesioned rat spinal cord following peripheral nerve stimulation [Paper]. Photons and Neurons, San Jose, California.
  - Gagnon, C., Desjardins-Crépeau, L., Desjardins, M., Tournier, I., Lesage, F., & Bherer, L. (2009, July). The acute effects of glucose on divided attention in older adults : A near-infrared spectroscopy [Paper]. XIXth IAGG World Congress of Gerontology and Geriatrics, Paris.
  - Cohen-Adad, J., Gauthier, C., Brooks, J. C. W., Leblond, H., Hoge, R. D., Fisher, J. A., Beaumont, E., Dubeau, S., Lesage, F., Doyon, J., Benali, H., & Rossignol, S. (2009, June). Venous effect in spinal cord fMRI : insights from intrinsic optical imaging and laser speckle [Paper]. 15th OHBM annual meeting, San Francisco, California.
- 2008
  - Lesage, F., Gagnon, L., & Dehaes, M. (2008, January). Diffuse optical-MRI fusion and applications [Paper]. Multimodal Biomedical Imaging III.
  - Kobayashi, M., Shih, J. L., Jen, C.-K., Ono, Y., & Lesage, F. (2008, June). Flexible ultrasonic transducers and their performance [Paper]. 31st Canadian Medical and Biological Engineering Conference, Montréal, Québec.
  - Delorme, J.-F., Ma, G., Lesage, F., Leblond, F., & Benyamin-Seyar, A. (2008, January). Full path Monte Carlo simulation of fluorescence in non-voxelized complex heterogeneous mouse model [Paper]. Optical Interactions with Tissue and Cells XIX, San Jose, CA, United states.
  - Brieu, N., Beaumont, E., & Lesage, F. (2008, March). Intrinsic optical imaging of the rat lumbar spinal cord [Paper]. OSA Biomed 2008, St. Petersburg, FL, USA.
  - Gagnon, L., Selb, J., Boas, D., Hoge, R., & Lesage, F. (2008, March). Measurements of haemoglobin concentrations in the human forehead using time-resolved reflectance [Paper]. OSA Biomed 2008, St. Petersburg, FL, USA.
  - Abran, M., Ono, Y., Jen, C.-K., Kobayashi, M., & Lesage, F. (2008, June). Multi-modal acoustic-photo-acoustic imaging for small animal imaging [Paper]. 31st Canadian Medical and Biological Engineering Conference, Montréal, Québec.
  - Matteau-Pelletier, C., Dehaes, M., Lesage, F., & Lina, J. M. (2008, May). Wavelet-based estimation of long-memory noise in diffuse optical imaging [Paper]. IEEE International Symposium on Biomedical Imaging: From Macro to Nano (ISBI '08), Paris, France.
- 2007
  - Provost, J., & Lesage, F. (2007, June). Compressive sampling in photo-acoustic imaging [Paper]. Photonics North 2007, Ottawa, On..
  - Scherer, L. C., Ska, B., Giroux, F., Lesage, F., Senhadji, N., Marcotte, K., Benali, H., & Joanette, Y. (2007, July). Investigating Narrative Discourse Abilities in Successful Aging: A Neuroimaging Study Using NIRS [Abstract]. International Neuropsychological Society, Federation of Spanish Societies of Neuropsychology, Spanish Neuropsychological Society, Spanish Psychiatry Society Joint Mid-Year Meeting, Bilbao, Spain. Published in Journal of the International Neuropsychological Society, 13(S2).
  - Kahlaoui, K., Vlasblom, V., Lesage, F., Senhadji, N., Benali, H., & Joanette, Y. (2007, July). Maintaining the ability to semantically process words with age: a near-infrared spectroscopy study [Abstract]. International Neuropsychological Society, Federation of Spanish Societies of Neuropsychology, Spanish Neuropsychological Society, Spanish Psychiatry Society Joint Mid-Year Meeting, Bilbao, Spain. Published in Journal of the International Neuropsychological Society, 13(S2).
  - Dehaes, M., Lesage, F., & Comeau, R. M. (2007, April). MRI/DOI neuronavigation: Revisiting the negative bold signal through diffuse optical imaging [Paper]. IEEE International Symposium on Biomedical Imaging : From Nano to Macro, Arlington, VA, United States.
- 2006
  - Kahlaoui, K., Lesage, F., Senhadji, N., Benali, H., & Joanette, Y. (2006, June). Hemispheric specialization for the semantic processing of words analyzed by near-infrared spectroscopy [Abstract]. 12th Annual Meeting of the Organization for Human Brain Mapping, Florence, Italy. Published in NeuroImage, 31(S1).
  - Dehaes, M., Comeau, R., & Lesage, F. (2006, June). MRI/DOI Neuronavigation [Abstract]. 12th Annual Meeting of the Organization for Human Brain Mapping, Florence, Italy. Published in NeuroImage, 31(S1).
  - Scherer, L. C., Giroux, F., Lesage, F., Senhadji, N., Benalki, H., & Ansaldo, A. I. (2006, June). Processing of Syntax and Semantics by Elderly Bilinguals : An Optical Imaging Study [Abstract]. 12th Annual Meeting of the Organization for Human Brain Mapping, Florence, Italy. Published in NeuroImage, 31(S1).
  - Scherer, L. C., Giroux, F., Lesage, F., Senhadi, N., Ska, B., Benali, H., & Joanette, Y. (2006, June). The impact of aging and language proficiency on the interhemispheric dynamics for discourse processing [Abstract]. 12th Annual Meeting of the Organization for Human Brain Mapping, Florence, Italy. Published in NeuroImage, 31(S1).
Book chapters (2)
- 2014
  - Bélanger, S., de Souza, B. O. F., Pouliot, P., Casanova, C., & Lesage, F. (2014). Neurovascular Coupling in the Deep Brain Using Confocal Fiber-Optic Endomicroscopy. In Neuromethods (Vol. 88, 77-95).
- 2013
  - Kamrani, E., Lesage, F., & Sawan, M. (2013). Near-infrared light detection using CMOS silicon avalanche photodiodes (SiAPDs). In The Wonder of Nanotechnology: Quantum Optoelectronic Devices and Applications (491-531).
Patents (2)
- 2015
  - Goguin, A., Lesage, F., Rossignol, S., & Benali, H. (2015). Device for measuring the activity of the spinal cord of a vertebra. (Patent no. US9107580).
  - Lesage, F., Bélanger, S., Abran, M., & Provost, J. (2015). Method and system for optical data acquisition and tomography imaging of a turbid medium object. (Patent no. US9134229).

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Lesage, Frédéric

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Lesage, Frédéric

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Frédéric Lesage (306)